ID E6UAI9_RUMA7 Unreviewed; 260 AA.
AC E6UAI9;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Short-chain dehydrogenase/reductase SDR {ECO:0000313|EMBL:ADU22411.1};
GN OrderedLocusNames=Rumal_1917 {ECO:0000313|EMBL:ADU22411.1};
OS Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 /
OS 7).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=697329 {ECO:0000313|EMBL:ADU22411.1, ECO:0000313|Proteomes:UP000006919};
RN [1] {ECO:0000313|EMBL:ADU22411.1, ECO:0000313|Proteomes:UP000006919}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7
RC {ECO:0000313|Proteomes:UP000006919};
RX PubMed=21914885; DOI=10.1128/JB.05621-11;
RA Suen G., Stevenson D.M., Bruce D.C., Chertkov O., Copeland A., Cheng J.F.,
RA Detter C., Detter J.C., Goodwin L.A., Han C.S., Hauser L.J., Ivanova N.N.,
RA Kyrpides N.C., Land M.L., Lapidus A., Lucas S., Ovchinnikova G.,
RA Pitluck S., Tapia R., Woyke T., Boyum J., Mead D., Weimer P.J.;
RT "Complete genome of the cellulolytic ruminal bacterium Ruminococcus albus
RT 7.";
RL J. Bacteriol. 193:5574-5575(2011).
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002403; ADU22411.1; -; Genomic_DNA.
DR AlphaFoldDB; E6UAI9; -.
DR STRING; 697329.Rumal_1917; -.
DR KEGG; ral:Rumal_1917; -.
DR eggNOG; COG1028; Bacteria.
DR HOGENOM; CLU_010194_1_0_9; -.
DR Proteomes; UP000006919; Chromosome.
DR GO; GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.
DR CDD; cd05233; SDR_c; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR42760:SF40; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE; 1.
DR PANTHER; PTHR42760; SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER; 1.
DR Pfam; PF00106; adh_short; 1.
DR Pfam; PF13561; adh_short_C2; 1.
DR PRINTS; PR00081; GDHRDH.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023221};
KW Steroid metabolism {ECO:0000256|ARBA:ARBA00023221}.
SQ SEQUENCE 260 AA; 28661 MW; BD1F89021610E3FB CRC64;
MGLEAAKAMP NDRIFLLSGR TIQKLDNAAR LLKADDKQTY IMPCDTSDRK QVHELARYAA
SLGEVTNVIH SAGLSPSIAE PEKLLRVNAL GTVYVNSEFA KVMKKGVIVD ISSNSAYQLP
KFMVPKGIYT LAEKDEAKFL VKLLRMCRFV KDSYKSSGLA YALSKNFVIW YAKKSAFEYG
SCGIRICSLS PGLIATDMGE CEKNEGSSML RYTAEKRMGT PEELGFAIAM AADERNGYLT
GVDILVDGGS VNGKYYQRKE
//
