ID E6UCD0_RUMA7 Unreviewed; 334 AA.
AC E6UCD0;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:ADU20722.1};
GN OrderedLocusNames=Rumal_0165 {ECO:0000313|EMBL:ADU20722.1};
OS Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 /
OS 7).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=697329 {ECO:0000313|EMBL:ADU20722.1, ECO:0000313|Proteomes:UP000006919};
RN [1] {ECO:0000313|EMBL:ADU20722.1, ECO:0000313|Proteomes:UP000006919}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7
RC {ECO:0000313|Proteomes:UP000006919};
RX PubMed=21914885; DOI=10.1128/JB.05621-11;
RA Suen G., Stevenson D.M., Bruce D.C., Chertkov O., Copeland A., Cheng J.F.,
RA Detter C., Detter J.C., Goodwin L.A., Han C.S., Hauser L.J., Ivanova N.N.,
RA Kyrpides N.C., Land M.L., Lapidus A., Lucas S., Ovchinnikova G.,
RA Pitluck S., Tapia R., Woyke T., Boyum J., Mead D., Weimer P.J.;
RT "Complete genome of the cellulolytic ruminal bacterium Ruminococcus albus
RT 7.";
RL J. Bacteriol. 193:5574-5575(2011).
CC -!- SIMILARITY: Belongs to the radical SAM superfamily. Anaerobic
CC sulfatase-maturating enzyme family. {ECO:0000256|ARBA:ARBA00023601}.
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DR EMBL; CP002403; ADU20722.1; -; Genomic_DNA.
DR RefSeq; WP_013496914.1; NZ_JHYT01000003.1.
DR AlphaFoldDB; E6UCD0; -.
DR STRING; 697329.Rumal_0165; -.
DR KEGG; ral:Rumal_0165; -.
DR eggNOG; COG0641; Bacteria.
DR HOGENOM; CLU_009273_3_0_9; -.
DR OrthoDB; 9808591at2; -.
DR Proteomes; UP000006919; Chromosome.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023867; Sulphatase_maturase_rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR43273; ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED; 1.
DR PANTHER; PTHR43273:SF8; RADICAL SAM PROTEIN-RELATED; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDG01072; dehydrogenase_like; 1.
DR SFLD; SFLDG01384; thioether_bond_formation_requi; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 1..218
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 334 AA; 38457 MW; 91D1A64B63664695 CRC64;
MHVVFWTTND CNLNCSYCYN RMSNNIKKEY MTREVADAAI DMLTKLDCWK TADEIAVQFH
GGEPLMNCDI IEYIMERFEA LVPASKLYYG MTTNGTLYDD RRKKIIDKIN ELSLSLDGKA
EIHDLNRKFV SGKGSFDIVM DTARDISKRK DVRLRMTVTR DTIGDLCDTV CYFLEEGFRR
IIPVLDMYDS HWKDEDEPII FEQFRKIKEY IEEKDYGDAV ISYVTESEFV RKAKCTGGVE
SFHFLPDGSI YPCSLTVGDS YWLLGNVLDT GLDKAKVDEL QMINNKDTSS CTGCEMYHYC
ASSRCKLINK KITGDYYTAS SIACLCSRLE YEFA
//
