ID E6UUV1_VARPE Unreviewed; 284 AA.
AC E6UUV1;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=6-phosphogluconate dehydrogenase NAD-binding protein {ECO:0000313|EMBL:ADU36366.1};
GN OrderedLocusNames=Varpa_2160 {ECO:0000313|EMBL:ADU36366.1};
OS Variovorax paradoxus (strain EPS).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=595537 {ECO:0000313|EMBL:ADU36366.1, ECO:0000313|Proteomes:UP000008917};
RN [1] {ECO:0000313|Proteomes:UP000008917}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EPS {ECO:0000313|Proteomes:UP000008917};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Ovchinnikova G., Orwin P., Han J.-I.G., Woyke T.;
RT "Complete sequence of Variovorax paradoxus EPS.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADU36366.1, ECO:0000313|Proteomes:UP000008917}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EPS {ECO:0000313|EMBL:ADU36366.1,
RC ECO:0000313|Proteomes:UP000008917};
RX PubMed=24158554;
RA Han J.I., Spain J.C., Leadbetter J.R., Ovchinnikova G., Goodwin L.A.,
RA Han C.S., Woyke T., Davenport K.W., Orwin P.M.;
RT "Genome of the Root-Associated Plant Growth-Promoting Bacterium Variovorax
RT paradoxus Strain EPS.";
RL Genome Announc. 1:e00843-e00813(2013).
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DR EMBL; CP002417; ADU36366.1; -; Genomic_DNA.
DR RefSeq; WP_013540601.1; NC_014931.1.
DR AlphaFoldDB; E6UUV1; -.
DR STRING; 595537.Varpa_2160; -.
DR KEGG; vpe:Varpa_2160; -.
DR eggNOG; COG2084; Bacteria.
DR HOGENOM; CLU_035117_2_1_4; -.
DR OrthoDB; 9786703at2; -.
DR Proteomes; UP000008917; Chromosome.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR048666; RedAm-like_C.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR Pfam; PF21761; RedAm-like_C; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
FT DOMAIN 4..157
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 161..284
FT /note="NADPH-dependent reductive aminase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21761"
SQ SEQUENCE 284 AA; 29540 MW; 2C85D513DA050798 CRC64;
MTDVSLIGLG PMGIALARAL QSKFTLTVWN RTAERAKPLL NQGTVLAPGA LAAVQASPVV
LVCVADYTAW RAILAAPGVA DALRGKVLVQ LSTGTPQDAR DDWAALGGVA YLDGALLATP
GQIGRPDTPL FISGEERALA ACRPVLEAIA GNIQYMGEPI GNAAAWDLAT LSCMFGAMSG
FFHGVRICES EGLGVAAFSQ MIGAISPVLG EMISAEGLAI HADRYGEPES SMATCAGAGR
LFVKQAREAG LDASFPDFLM GLFKRSLDAG FANERLAAMV KVMR
//
