ID E6UVA0_VARPE Unreviewed; 433 AA.
AC E6UVA0;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=TRAP transporter large permease protein {ECO:0000256|RuleBase:RU369079};
GN OrderedLocusNames=Varpa_4527 {ECO:0000313|EMBL:ADU38694.1};
OS Variovorax paradoxus (strain EPS).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=595537 {ECO:0000313|EMBL:ADU38694.1, ECO:0000313|Proteomes:UP000008917};
RN [1] {ECO:0000313|Proteomes:UP000008917}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EPS {ECO:0000313|Proteomes:UP000008917};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Ovchinnikova G., Orwin P., Han J.-I.G., Woyke T.;
RT "Complete sequence of Variovorax paradoxus EPS.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADU38694.1, ECO:0000313|Proteomes:UP000008917}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EPS {ECO:0000313|EMBL:ADU38694.1,
RC ECO:0000313|Proteomes:UP000008917};
RX PubMed=24158554;
RA Han J.I., Spain J.C., Leadbetter J.R., Ovchinnikova G., Goodwin L.A.,
RA Han C.S., Woyke T., Davenport K.W., Orwin P.M.;
RT "Genome of the Root-Associated Plant Growth-Promoting Bacterium Variovorax
RT paradoxus Strain EPS.";
RL Genome Announc. 1:e00843-e00813(2013).
CC -!- FUNCTION: Part of the tripartite ATP-independent periplasmic (TRAP)
CC transport system. {ECO:0000256|RuleBase:RU369079}.
CC -!- SUBUNIT: The complex comprises the extracytoplasmic solute receptor
CC protein and the two transmembrane proteins.
CC {ECO:0000256|RuleBase:RU369079}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU369079}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU369079}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TRAP transporter large permease family.
CC {ECO:0000256|RuleBase:RU369079}.
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DR EMBL; CP002417; ADU38694.1; -; Genomic_DNA.
DR RefSeq; WP_013542904.1; NC_014931.1.
DR AlphaFoldDB; E6UVA0; -.
DR STRING; 595537.Varpa_4527; -.
DR KEGG; vpe:Varpa_4527; -.
DR eggNOG; COG1593; Bacteria.
DR HOGENOM; CLU_019824_4_0_4; -.
DR OrthoDB; 9796052at2; -.
DR Proteomes; UP000008917; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR010656; DctM.
DR InterPro; IPR004681; TRAP_DctM.
DR NCBIfam; TIGR00786; dctM; 1.
DR PANTHER; PTHR33362:SF5; C4-DICARBOXYLATE TRAP TRANSPORTER LARGE PERMEASE PROTEIN DCTM; 1.
DR PANTHER; PTHR33362; SIALIC ACID TRAP TRANSPORTER PERMEASE PROTEIN SIAT-RELATED; 1.
DR Pfam; PF06808; DctM; 1.
DR PIRSF; PIRSF006066; HI0050; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519,
KW ECO:0000256|RuleBase:RU369079};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU369079};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU369079};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU369079}; Transport {ECO:0000256|RuleBase:RU369079}.
FT TRANSMEM 6..39
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 60..81
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 101..129
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 141..168
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 180..201
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 248..266
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 278..299
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 311..333
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 340..359
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 365..392
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT TRANSMEM 404..428
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU369079"
FT DOMAIN 11..423
FT /note="TRAP C4-dicarboxylate transport system permease DctM
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF06808"
SQ SEQUENCE 433 AA; 45889 MW; 4BCB0E2AAFA6467F CRC64;
MSPDAVAILG FVALFVLMLL RVPVGMAMGL VGVVGYSYLV GPGPALKLVG QTSMRTVTDY
TFGVIPMFML MGALVSVSGV SRELFKAANS MIGHLRGGLG VATVVACGGF AAICGSSVAT
AATFSAVAYP EMRRFNYPQS FSTGVIAAGG TLGAILPPST VLAVYAILTQ QDIGKLFMAG
IVPGILAMAM YVLTIAIIVK LRPDWLPGGE VKPWSERFKD LRNVWAPLVL FVFVIGGLYG
GFFTPTEAGG VGASGAFILG LVRRKLDGPK IREALLSATR TAAAVFTVLI GALLFGYFLT
ITQSPQKLTE FLTGLGIGRY GVLALIMVMY LVLGCLMDAM AMIILTVPII FPVIVHLGFD
PIWFGVIIVM TVELGLIHPP VGMNVFVIKS VVKDVSFTTI FKGVLPFIVT DIVRLVILIA
FPVIALWLPT RMG
//
