ID E6YEB8_9NEOP Unreviewed; 366 AA.
AC E6YEB8;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=Elongation factor 1-alpha {ECO:0000256|RuleBase:RU000325};
DE Flags: Fragment;
GN Name=ef1a {ECO:0000313|EMBL:CBI70539.1};
OS Notoperata sp. NHRS CW6.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Trichoptera; Integripalpia; Brevitentoria;
OC Leptoceroidea; Leptoceridae; Triplectidinae; Hudsonemini; Notoperata.
OX NCBI_TaxID=699986 {ECO:0000313|EMBL:CBI70539.1};
RN [1] {ECO:0000313|EMBL:CBI70539.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21226926; DOI=10.1186/1471-2148-11-10;
RA Malm T., Johanson K.A.;
RT "A new classification of the long-horned caddisflies (Trichoptera:
RT Leptoceridae) based on molecular data.";
RL BMC Evol. Biol. 11:10-10(2011).
CC -!- FUNCTION: This protein promotes the GTP-dependent binding of aminoacyl-
CC tRNA to the A-site of ribosomes during protein biosynthesis.
CC {ECO:0000256|ARBA:ARBA00003982, ECO:0000256|RuleBase:RU000325}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249,
CC ECO:0000256|RuleBase:RU000325}.
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DR EMBL; FN600774; CBI70539.1; -; Genomic_DNA.
DR AlphaFoldDB; E6YEB8; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd03693; EF1_alpha_II; 1.
DR CDD; cd03705; EF1_alpha_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR004539; Transl_elong_EF1A_euk/arc.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR NCBIfam; TIGR00483; EF-1_alpha; 1.
DR PANTHER; PTHR23115:SF236; ELONGATION FACTOR 1-ALPHA 1; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000256|RuleBase:RU000325};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU000325};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000325};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Protein biosynthesis {ECO:0000256|RuleBase:RU000325}.
FT DOMAIN 1..196
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CBI70539.1"
FT NON_TER 366
FT /evidence="ECO:0000313|EMBL:CBI70539.1"
SQ SEQUENCE 366 AA; 39846 MW; 3DE333661DB45138 CRC64;
QEMGKGSFKY AWVLDKLKAE RERGITIDIA LWKFETAKYY VTIIDAPGHR DFIKNMITGT
SQADCAVLIV AAGTGEFEAG ISKNGQTREH ALLAFTLGVK QLIVGVNKMD STEPPYSEPR
FEEIKKEVSS YIKKIGYNPA AVAFVPISGW HGDNMLEPSS KMPWFKGWQV ERKEGKADGK
CLIEALDAIL PPARPTDKPL RLPLQDVYKI GGIGTVPVGR VETGVLKPGT IVVFAPANIT
TEVKSVEMHH EALPEAVPGD NVGFNVKNVS VKELRRGYVA GDSKNNPPKG AADFTAQVIV
LNHPGQISNG YTPVLDCHTA HIACKFSEIK EKVDRRTGKS TEDNPKAIKS GDAAIVILVP
SKPMCV
//
