ID E6YG31_BARC7 Unreviewed; 209 AA.
AC E6YG31;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Cytochrome bo(3) ubiquinol oxidase subunit 4 {ECO:0000256|ARBA:ARBA00014689};
DE AltName: Full=Cytochrome o ubiquinol oxidase subunit 4 {ECO:0000256|ARBA:ARBA00032185};
DE AltName: Full=Oxidase bo(3) subunit 4 {ECO:0000256|ARBA:ARBA00030071};
DE AltName: Full=Ubiquinol oxidase polypeptide IV {ECO:0000256|ARBA:ARBA00030211};
DE AltName: Full=Ubiquinol oxidase subunit 4 {ECO:0000256|ARBA:ARBA00031887};
GN Name=cyoD {ECO:0000313|EMBL:CBI75819.1};
GN OrderedLocusNames=BARCL_0138 {ECO:0000313|EMBL:CBI75819.1};
OS Bartonella clarridgeiae (strain CCUG 45776 / CIP 104772 / 73).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Bartonellaceae; Bartonella.
OX NCBI_TaxID=696125 {ECO:0000313|EMBL:CBI75819.1, ECO:0000313|Proteomes:UP000009101};
RN [1] {ECO:0000313|Proteomes:UP000009101}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIP 104772 / 73 {ECO:0000313|Proteomes:UP000009101};
RA Engel P., Salzburger W., Marius L., Chao-Chin C., Soichi M., Christa L.,
RA Alexandra C., Aurelie L., Claudine M., Stephan S.C., Christoph D.;
RT "Genome sequencing of Bartonella species and comparative genomics.";
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBI75819.1, ECO:0000313|Proteomes:UP000009101}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIP 104772 / 73 {ECO:0000313|Proteomes:UP000009101};
RX PubMed=21347280; DOI=10.1371/journal.pgen.1001296;
RA Engel P., Salzburger W., Liesch M., Chang C.C., Maruyama S., Lanz C.,
RA Calteau A., Lajus A., Medigue C., Schuster S.C., Dehio C.;
RT "Parallel evolution of a type IV secretion system in radiating lineages of
RT the host-restricted bacterial pathogen Bartonella.";
RL PLoS Genet. 7:E1001296-E1001296(2011).
CC -!- FUNCTION: Cytochrome bo(3) ubiquinol terminal oxidase is the component
CC of the aerobic respiratory chain of E.coli that predominates when cells
CC are grown at high aeration. Has proton pump activity across the
CC membrane in addition to electron transfer, pumping 2 protons/electron.
CC {ECO:0000256|ARBA:ARBA00025694}.
CC -!- SUBUNIT: Heterooctamer of two A chains, two B chains, two C chains and
CC two D chains. {ECO:0000256|ARBA:ARBA00011700}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the cytochrome c oxidase bacterial subunit 4
CC family. {ECO:0000256|ARBA:ARBA00008079}.
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DR EMBL; FN645454; CBI75819.1; -; Genomic_DNA.
DR AlphaFoldDB; E6YG31; -.
DR STRING; 696125.BARCL_0138; -.
DR KEGG; bcd:BARCL_0138; -.
DR eggNOG; COG3125; Bacteria.
DR HOGENOM; CLU_073789_0_0_5; -.
DR Proteomes; UP000009101; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0009486; F:cytochrome bo3 ubiquinol oxidase activity; IEA:InterPro.
DR GO; GO:0015990; P:electron transport coupled proton transport; IEA:InterPro.
DR InterPro; IPR005171; Cyt_c_oxidase_su4_prok.
DR InterPro; IPR014210; Cyt_o_ubiqinol_oxidase_su4.
DR NCBIfam; TIGR02847; CyoD; 1.
DR PANTHER; PTHR36835; CYTOCHROME BO(3) UBIQUINOL OXIDASE SUBUNIT 4; 1.
DR PANTHER; PTHR36835:SF1; CYTOCHROME BO(3) UBIQUINOL OXIDASE SUBUNIT 4; 1.
DR Pfam; PF03626; COX4_pro; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:CBI75819.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 13..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 137..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..199
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 209 AA; 23093 MW; 5116BB7358463BD1 CRC64;
MMSTDKKTHN PSIGSYLVGF ILAVLFTLGS FIPVMYGLLD SWAISTKVIY LIGMALIQII
VQIVFFLHLN SGPDAKWNIV TLLFTAMCVF VIIGGTWWAI SHLNYNMMGG SGRIIEPKIN
TTIPEDIPEE EFIGVPDSME QSSETSEPVE QSSETSEPVE QSSETSKSVE QSSETSEPVE
QSSETSEPVE QSSERLSIDS LPDRSYLKD
//
