ID E6ZK39_SPORE Unreviewed; 1201 AA.
AC E6ZK39;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Related to DNA topoisomerase II binding protein {ECO:0000313|EMBL:CBQ67692.1};
GN ORFNames=sr11642 {ECO:0000313|EMBL:CBQ67692.1};
OS Sporisorium reilianum (strain SRZ2) (Maize head smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Sporisorium.
OX NCBI_TaxID=999809 {ECO:0000313|EMBL:CBQ67692.1, ECO:0000313|Proteomes:UP000008867};
RN [1] {ECO:0000313|EMBL:CBQ67692.1, ECO:0000313|Proteomes:UP000008867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRZ2 {ECO:0000313|Proteomes:UP000008867};
RX PubMed=21148393; DOI=10.1126/science.1195330;
RA Schirawski J., Mannhaupt G., Muench K., Brefort T., Schipper K.,
RA Doehlemann G., Di Stasio M., Roessel N., Mendoza-Mendoza A., Pester D.,
RA Mueller O., Winterberg B., Meyer E., Ghareeb H., Wollenberg T.,
RA Muensterkoetter M., Wong P., Walter M., Stukenbrock E., Gueldener U.,
RA Kahmann R.;
RT "Pathogenicity determinants in smut fungi revealed by genome comparison.";
RL Science 330:1546-1548(2010).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; FQ311430; CBQ67692.1; -; Genomic_DNA.
DR AlphaFoldDB; E6ZK39; -.
DR EnsemblFungi; CBQ67692; CBQ67692; sr11642.
DR VEuPathDB; FungiDB:sr11642; -.
DR eggNOG; KOG1929; Eukaryota.
DR HOGENOM; CLU_273116_0_0_1; -.
DR OrthoDB; 20296at2759; -.
DR Proteomes; UP000008867; Chromosome 1.
DR GO; GO:0005694; C:chromosome; IEA:UniProt.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR CDD; cd00027; BRCT; 1.
DR CDD; cd17731; BRCT_TopBP1_rpt2_like; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 5.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR PANTHER; PTHR13561; DNA REPLICATION REGULATOR DPB11-RELATED; 1.
DR PANTHER; PTHR13561:SF20; DNA TOPOISOMERASE 2-BINDING PROTEIN 1; 1.
DR Pfam; PF12738; PTCB-BRCT; 2.
DR SMART; SM00292; BRCT; 5.
DR SUPFAM; SSF52113; BRCT domain; 4.
DR PROSITE; PS50172; BRCT; 4.
PE 4: Predicted;
KW Isomerase {ECO:0000313|EMBL:CBQ67692.1}.
FT DOMAIN 70..142
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 162..272
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 508..575
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 591..671
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 323..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 372..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 684..721
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 836..855
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 873..903
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1011..1043
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1114..1201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 336..350
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..458
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..704
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1201 AA; 129618 MW; 4B26BBDD53A45940 CRC64;
MNRSARAHRS TKIPNVKLRP AQRDSAATSA KRSRQHDELL DDREDAAHFR RLRDDGRDHG
AHLDSDFIGS SARPLKGAII SITGLGDTKA TLTQYARELG ARVEGNLTED VTHLIADRPG
SEKYRFALEL GMHIVSPDWI LEVRQAWLAG EDVDAEQLEH QHQLPALSNT TICFSALAGA
QRRTLVALAT ELGATVSDEL RFDGTITHLV SASADPNASS SVHHLLHFLD RARHGRNGTR
EQAASRILAV RPEWLQDCQR AAGCLSEQIY SIFAKLPDQK ERSALVEKAQ TKLPSPFVRQ
QDPVAVAFQG PFVASNRSQL ALIESDSGTR NSRNTDASHA LDEDDEQPIT LGSRQKAAAA
AEKSFDNILS QLKSNQPSSK PTTRAPAIPL ASDAPVTSTS SASASTSPNA PPSALPSAPT
STSAPFNTHR KSLLGMSRAS SFSPAPAPSA TSTAAPLNMR KTSSKLITLP HSSQATATQS
SNHSPSQPCF HTKSFKVCLN DEHRKKVLEQ VLRDNGATLL HVSLATSPDF VVVEPKASPA
SIRALDDAHV VPVLHFWIEY CLHHETFVEP HEYFAALPAR VPLPLHDGGQ LRLLLLGFDP
DSPELYHAQK LVAEMGGSVA KQIKGESLTH VICATQESFD GRRAQRARSC GVPVVGLEFI
IKARQTGRLV PPPIAIAIPE QSSSALTPSS NSNSNSTALN SNAAAVPATE HHEQAGSVAK
QPDLPLAGCT VSRSKVLASQ SVMLERKALQ LGACWQAQAN ESTTHLLHRG AGLPREAKDL
ESGAFLVHPT WLDKCIEQAI RVDEGLFPSS MDPSRSLLTV LSNSDGSATG NFLSQASQST
MQRKAKPQAA QASQQQTQAE LVAAAKPWHR SISADAARRT IDVDPIDGDG PGNAPRSRGR
SEEIETVHDV LQDDETNELV RDVDFDADVT LSGHAPDSHL GMDVDDAAPA PSSQTLFEGE
EAVDDDAPVG EVRGTNPSAP FKQVDLLKKA KDQIASADEV MELLRSRTLA QGARKKNRLP
PRARKQRPDE IKSTATSGTE GGMLAPEKVL EAQAQLDAQR AAEAAAQGYS LGMDKDVALP
PNSQTGAGFD ASIRIVYDDP AALRERNKLL KMLDHHQQQQ QQHHQPARGM DDTVAIDAGD
ETEDIQMDDS VGGAAQANGS RKRGSEDTFG AGRQSRHYWE NRNSESPTKR PVVRRQPLAR
R
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