ID E6ZVN9_SPORE Unreviewed; 651 AA.
AC E6ZVN9;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Related to deoxyribodipyrimidine photo-lyase PHR {ECO:0000313|EMBL:CBQ71357.1};
GN ORFNames=sr16705 {ECO:0000313|EMBL:CBQ71357.1};
OS Sporisorium reilianum (strain SRZ2) (Maize head smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Sporisorium.
OX NCBI_TaxID=999809 {ECO:0000313|EMBL:CBQ71357.1, ECO:0000313|Proteomes:UP000008867};
RN [1] {ECO:0000313|EMBL:CBQ71357.1, ECO:0000313|Proteomes:UP000008867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRZ2 {ECO:0000313|Proteomes:UP000008867};
RX PubMed=21148393; DOI=10.1126/science.1195330;
RA Schirawski J., Mannhaupt G., Muench K., Brefort T., Schipper K.,
RA Doehlemann G., Di Stasio M., Roessel N., Mendoza-Mendoza A., Pester D.,
RA Mueller O., Winterberg B., Meyer E., Ghareeb H., Wollenberg T.,
RA Muensterkoetter M., Wong P., Walter M., Stukenbrock E., Gueldener U.,
RA Kahmann R.;
RT "Pathogenicity determinants in smut fungi revealed by genome comparison.";
RL Science 330:1546-1548(2010).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR602081-1};
CC Note=Binds 1 FAD per subunit. {ECO:0000256|PIRSR:PIRSR602081-1};
CC -!- SIMILARITY: Belongs to the DNA photolyase class-1 family.
CC {ECO:0000256|ARBA:ARBA00005862}.
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DR EMBL; FQ311443; CBQ71357.1; -; Genomic_DNA.
DR AlphaFoldDB; E6ZVN9; -.
DR EnsemblFungi; CBQ71357; CBQ71357; sr16705.
DR VEuPathDB; FungiDB:sr16705; -.
DR eggNOG; KOG0133; Eukaryota.
DR HOGENOM; CLU_010348_2_1_1; -.
DR OrthoDB; 124765at2759; -.
DR Proteomes; UP000008867; Chromosome 21.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.80; -; 1.
DR Gene3D; 1.10.579.10; DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR036134; Crypto/Photolyase_FAD-like_sf.
DR InterPro; IPR036155; Crypto/Photolyase_N_sf.
DR InterPro; IPR005101; Cryptochr/Photolyase_FAD-bd.
DR InterPro; IPR002081; Cryptochrome/DNA_photolyase_1.
DR InterPro; IPR006050; DNA_photolyase_N.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR11455; CRYPTOCHROME; 1.
DR PANTHER; PTHR11455:SF18; DEOXYRIBODIPYRIMIDINE PHOTO-LYASE, MITOCHONDRIAL; 1.
DR Pfam; PF00875; DNA_photolyase; 1.
DR Pfam; PF03441; FAD_binding_7; 1.
DR SUPFAM; SSF48173; Cryptochrome/photolyase FAD-binding domain; 1.
DR SUPFAM; SSF52425; Cryptochrome/photolyase, N-terminal domain; 1.
DR PROSITE; PS51645; PHR_CRY_ALPHA_BETA; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR602081-1};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630, ECO:0000256|PIRSR:PIRSR602081-
KW 1}; Lyase {ECO:0000313|EMBL:CBQ71357.1}.
FT DOMAIN 120..263
FT /note="Photolyase/cryptochrome alpha/beta"
FT /evidence="ECO:0000259|PROSITE:PS51645"
FT REGION 1..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 399
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
FT BINDING 411..415
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
FT BINDING 451
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
FT BINDING 454..461
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
FT BINDING 552..554
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
FT SITE 486
FT /note="Electron transfer via tryptophanyl radical"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-2"
FT SITE 539
FT /note="Electron transfer via tryptophanyl radical"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-2"
FT SITE 562
FT /note="Electron transfer via tryptophanyl radical"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-2"
SQ SEQUENCE 651 AA; 72655 MW; 633A3981F50246AC CRC64;
MAASKRKDVS PKPEDHDEDE KALDPKLAEH PDEDEAETSK PPTKRKQTKG DRSAVINGGA
KADKQYGASA YAKSGDGWHR SDFNPSPCGR TDSQTPLDDL EAALKAHAPN KANDEGDGKN
VLYWMRMHDL RVHDNRALAH ASALAAARRA KGKGGNLIAL FVITPADYSA HDRGARRIDF
VLRTLASLKT QFDELDIPFV VYTHSGARTK VGEKVFDLCA KYSVSQLTAN IEYEVDELWR
DIGMLKAASA QNVAFSLFHD CYVVPPGRVR TNDGRPYSVF SPWNRRWTDC IAKDLSLIEA
SPDPEPNPKS IHKDSALSAL FDLSSLGAGY GIPTELPGFE CKDRAYMAKL WPVDGDAPQQ
VLDNFMAGKG GETALDRPAN EPSTAHVGGN AKDSRLGRYA EGRNLMDENG TSRISPYLAA
GLVSARECLR RTKALTKNRL TVGRDSGAAM WNTEISFRDF YGHVLAAWPK VCMGHAFITK
YEDVVWETDP KTLQAWKEGR TGYPIVDAAQ RQCIQQGYIH NRGRMISAMF LTKHLLHDWR
EGERHFSLNF IDQDFASNNG GWQWSASTGT DPQPYFRIFN LLSQSEKSDP QGDYIRHFVP
ELKNVKGKAI HDPFHRLSKP EFDKLGYPKP IVEHAEARQR ALRRYKSPGD K
//
