ID E7ACG3_HELFC Unreviewed; 570 AA.
AC E7ACG3;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Methyl-accepting chemotaxis protein (TlpA) {ECO:0000313|EMBL:CBY82192.1};
GN OrderedLocusNames=Hfelis_01080 {ECO:0000313|EMBL:CBY82192.1};
OS Helicobacter felis (strain ATCC 49179 / NCTC 12436 / CS1).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=936155 {ECO:0000313|EMBL:CBY82192.1, ECO:0000313|Proteomes:UP000007934};
RN [1] {ECO:0000313|Proteomes:UP000007934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49179 / NCTC 12436 / CS1
RC {ECO:0000313|Proteomes:UP000007934};
RA Arnold A., Zigova Z., Lawley T., Falkow S., Bentley S., Aslett M.,
RA Muller A.;
RT "Comparative whole genome analysis of the carcinogenic bacterial pathogen
RT Helicobacter felis.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBY82192.1, ECO:0000313|Proteomes:UP000007934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49179 / NCTC 12436 / CS1
RC {ECO:0000313|Proteomes:UP000007934};
RX PubMed=21402865;
RA Arnold I.C., Zigova Z., Holden M., Lawley T.D., Rad R., Dougan G.,
RA Falkow S., Bentley S.D., Muller A.;
RT "Comparative whole genome sequence analysis of the carcinogenic bacterial
RT model pathogen Helicobacter felis.";
RL Genome Biol. Evol. 3:302-308(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; FQ670179; CBY82192.1; -; Genomic_DNA.
DR RefSeq; WP_013468562.1; NC_014810.2.
DR AlphaFoldDB; E7ACG3; -.
DR STRING; 936155.HFELIS_01080; -.
DR GeneID; 36134869; -.
DR KEGG; hfe:HFELIS_01080; -.
DR eggNOG; COG0840; Bacteria.
DR eggNOG; COG4564; Bacteria.
DR HOGENOM; CLU_000445_107_21_7; -.
DR Proteomes; UP000007934; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR004010; Double_Cache_2.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR033480; sCache_2.
DR PANTHER; PTHR32089:SF112; HEME-BASED AEROTACTIC TRANSDUCER HEMAT; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF08269; dCache_2; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM01049; Cache_2; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007934};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 196..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 350..570
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 570 AA; 64004 MW; 35CF61B2F41BA847 CRC64;
MLTIVVTVVT LFMFVHNNQT SIKQINEIVS TDFREMLRER LKLAVNSLNH SLSYAIEHIP
HEEDKKRVIN AMLRKFRFEK DNSGYFFAYD KYHVIYTSQA THYPMGTNLK DLQSKNGVLF
IQELYKVAMS GGGFVRYIFP KPSASGEMRD AEKVSYAEEI KGMPGWWIGA GVYTDNITAR
TQIIVDNINQ KLTNTFHIYI IIVLLFLLFV VIPAYYFFYR TLTGNIKALD GGLKDFFSFV
SYKKQGVPNP IQSHSKCELG QMARALNSSI QETVAHLQSD QKLSQEVLNA LDGARTGDFT
QNIHTQTTNP QLQYLGNNFN AFLVALKSIF YNISSTMQTY SKNDFRIGMD TANLRGGFLE
LANNINTLRT SIVSSLRNSL NFANALTQET HALNETTHAM DNASKQQTHS LEQTTQALEQ
ITRVTQSVHA KNREVIEQSE GIQRIVLTIT EIADQISLLA LNATIEAARA GEHGRGFAVV
ADEVRQLAER TQKSLGEIET NTQALTQSIN DATSAIEEQT QSIAQINVAM EELEQTVAHN
AQIAATSSTI SENVQRIAKN ILEEANNKKF
//
