ID   E7BLS0_9BRAS            Unreviewed;       376 AA.
AC   E7BLS0;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Chalcone synthase {ECO:0000313|EMBL:ADN93213.1};
DE   Flags: Fragment;
GN   Name=Chs {ECO:0000313|EMBL:ADN93213.1};
OS   Erysimum sisymbrioides.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Erysimeae; Erysimum.
OX   NCBI_TaxID=369002 {ECO:0000313|EMBL:ADN93213.1};
RN   [1] {ECO:0000313|EMBL:ADN93213.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Zhao B., Liu L., Tan D., Wang J.;
RT   "Analysis of phylogenetic relationships of Brassicaceae species based on
RT   Chs sequences.";
RL   Biochem. Syst. Ecol. 38:731-739(2010).
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC       synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC       ECO:0000256|RuleBase:RU003633}.
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DR   EMBL; GQ983012; ADN93213.1; -; Genomic_DNA.
DR   AlphaFoldDB; E7BLS0; -.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00831; CHS_like; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR   InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR   InterPro; IPR018088; Chalcone/stilbene_synthase_AS.
DR   InterPro; IPR011141; Polyketide_synthase_type-III.
DR   InterPro; IPR016039; Thiolase-like.
DR   PANTHER; PTHR11877:SF14; CHALCONE SYNTHASE; 1.
DR   PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR   Pfam; PF02797; Chal_sti_synt_C; 1.
DR   Pfam; PF00195; Chal_sti_synt_N; 1.
DR   PIRSF; PIRSF000451; PKS_III; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
DR   PROSITE; PS00441; CHALCONE_SYNTH; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW   Transferase {ECO:0000256|RuleBase:RU003633}.
FT   DOMAIN          3..226
FT                   /note="Chalcone/stilbene synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00195"
FT   DOMAIN          237..376
FT                   /note="Chalcone/stilbene synthase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02797"
FT   ACT_SITE        162
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ADN93213.1"
FT   NON_TER         376
FT                   /evidence="ECO:0000313|EMBL:ADN93213.1"
SQ   SEQUENCE   376 AA;  41166 MW;  036EBE724A3DE58B CRC64;
     SLDEIRKAQR ADGPAGILAI GTANPANHVI QAEYPDYYFR ITNSEHMTDL KEKFKRMCDK
     SMIRKRHMHL TEEFLKENPH MCAYMAPSLD TRQDIVVVEV PKLGKEAAVK AIKEWGQPKS
     KITHVVFCTT SGVDMPGADY QLTKLLGLRP SVKRLMMYQQ GCFAGGTVLR LAKDLAENNR
     GARVLVVCSE ITAVTFRGPS DTHLDSLVGQ ALFSDGAAAL IVGSDPDTSA GEKPIFEMVS
     AAQTILPDSD GAIDGHLREV GLTFHLLKDV PGLISKNIEK SLDEAFKPLG ISDWNSLFWI
     AHPGGPAILD QVEIKLGLKE EKMRATRHVL SEYGNMSSAC VLFILDEMRR KSAKDGVATT
     GEGLEWGVLF GFGPGL
//