ID   E7C655_9ACTN            Unreviewed;       205 AA.
AC   E7C655;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes {ECO:0000313|EMBL:ADI22929.1};
OS   uncultured actinobacterium HF0500_35G12.
OC   Bacteria; Actinomycetota; Actinomycetes; marine Actinobacteria clade;
OC   environmental samples.
OX   NCBI_TaxID=723604 {ECO:0000313|EMBL:ADI22929.1};
RN   [1] {ECO:0000313|EMBL:ADI22929.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Pham V.D., Delong E.F.;
RT   "Genome fragments of uncultured bacteria from the North Pacific subtropical
RT   Gyre.";
RL   Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC         Evidence={ECO:0000256|ARBA:ARBA00001938};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GU568001; ADI22929.1; -; Genomic_DNA.
DR   AlphaFoldDB; E7C655; -.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   PANTHER; PTHR43178; DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; 1.
DR   PANTHER; PTHR43178:SF5; LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL; 1.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
PE   4: Predicted;
KW   Acyltransferase {ECO:0000313|EMBL:ADI22929.1};
KW   Pyruvate {ECO:0000313|EMBL:ADI22929.1};
KW   Transferase {ECO:0000313|EMBL:ADI22929.1}.
FT   DOMAIN          2..197
FT                   /note="2-oxoacid dehydrogenase acyltransferase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00198"
SQ   SEQUENCE   205 AA;  22763 MW;  84CDCD3F6B114CA0 CRC64;
     MEVDYESVEA VRRVHRSQWK ESEGFSLTYL PFIIHAVARS LAEFPRINAS INDTDLVIHD
     EINIGVAVDL DFEGLVVPVI REVDQLPLTE LARQIVHVAE QARARKLAPD DMAGGTFTIT
     NAGPFGTLLQ FPIINQPQVA ILSTDGISRK PAVVTDTEGN ESIEIRSIGI LALAWDHRAF
     DGAYAASFLR RIRDLIEGTD WESEI
//