ID   E7D1Z3_MANSE            Unreviewed;       482 AA.
AC   E7D1Z3;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=GNBP-like protein {ECO:0000313|EMBL:ADT82662.1};
DE   Flags: Fragment;
OS   Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Sphingidae; Sphinginae; Sphingini; Manduca.
OX   NCBI_TaxID=7130 {ECO:0000313|EMBL:ADT82662.1};
RN   [1] {ECO:0000313|EMBL:ADT82662.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=21296155; DOI=10.1016/j.ibmb.2011.01.010;
RA   Wang Y., Sumathipala N., Rayaprolu S., Jiang H.;
RT   "Recognition of microbial molecular patterns and stimulation of
RT   prophenoloxidase activation by a beta-1,3-glucanase-related protein in
RT   Manduca sexta larval plasma.";
RL   Insect Biochem. Mol. Biol. 41:322-331(2011).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the insect beta-1,3-glucan binding protein
CC       family. {ECO:0000256|ARBA:ARBA00008781}.
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DR   EMBL; HQ007028; ADT82662.1; -; mRNA.
DR   AlphaFoldDB; E7D1Z3; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   CDD; cd02179; GH16_beta_GRP; 1.
DR   Gene3D; 2.60.120.200; -; 1.
DR   Gene3D; 2.60.40.2140; Beta-1,3-glucan-recognition protein, N-terminal domain; 1.
DR   InterPro; IPR031756; BGBP_N.
DR   InterPro; IPR043030; BGBP_N_sf.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR000757; GH16.
DR   InterPro; IPR035806; GH16_GRP_C.
DR   PANTHER; PTHR10963; GLYCOSYL HYDROLASE-RELATED; 1.
DR   PANTHER; PTHR10963:SF70; GRAM-NEGATIVE BACTERIA-BINDING PROTEIN 1-RELATED; 1.
DR   Pfam; PF15886; CBM39; 1.
DR   Pfam; PF00722; Glyco_hydro_16; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   PROSITE; PS51969; CBM39; 1.
DR   PROSITE; PS51762; GH16_2; 1.
PE   2: Evidence at transcript level;
KW   Immunity {ECO:0000256|ARBA:ARBA00022859};
KW   Innate immunity {ECO:0000256|ARBA:ARBA00022588};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..482
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003218558"
FT   DOMAIN          20..120
FT                   /note="CBM39"
FT                   /evidence="ECO:0000259|PROSITE:PS51969"
FT   DOMAIN          127..482
FT                   /note="GH16"
FT                   /evidence="ECO:0000259|PROSITE:PS51762"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ADT82662.1"
SQ   SEQUENCE   482 AA;  53687 MW;  83CC1774F3C8164B CRC64;
     AAWWCGRVIT LFLCVHLTVG QIPNVSIHAY KPKGFSVSIP DGQNIGLFAF HGNINRGINK
     NDVGTIAGEV LKAKNGMWIY EDPELELKVG DVINYYVFVS INSKGYLKDN LSFTVTKLED
     RSSVTGPIRP GTVLPEDCKP TRTKVRGGFA CAGQTLFEDN FDMLDESVWQ IEQYIPNTHP
     EYPFVSYQHL ATDQTVTTAG GTLRITPKLQ QDLPGFTNET ILSGTLNLFS GCTSSADSCL
     IQVDGADILP PVASGRITSK TFAFTYGKVY VRAKLPQGDW LYPEILLEPF LHKYGSLHYS
     SGVIKIATAR GNRQLYYGPN DYSNKVLYGG PIMDLACRET LLSTKLRRDG SAWGDDFHLY
     SLEWTPEHIV LMVDDEEWAR VEPTASGLRG QFPASCRQLP QMLLRAGTSM APFDDYFYLT
     LGVAAGSITE FPDGSVTVGD RIKPWRNSAR KAMLNFWQDT NSWLPTWLLS RLEVDYVKVV
     AL
//