ID   E7DX25_PICGL            Unreviewed;       836 AA.
AC   E7DX25;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Class III homeodomain leucine zipper protein {ECO:0000313|EMBL:ADV04323.1};
GN   Name=HB4 {ECO:0000313|EMBL:ADV04323.1};
OS   Picea glauca (White spruce) (Pinus glauca).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Pinopsida; Pinidae; Conifers I; Pinales; Pinaceae; Picea.
OX   NCBI_TaxID=3330 {ECO:0000313|EMBL:ADV04323.1};
RN   [1] {ECO:0000313|EMBL:ADV04323.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=21143995; DOI=10.1186/1471-2229-10-273;
RA   Cote C.L., Boileau F., Roy V., Ouellet M., Levasseur C., Morency M.J.,
RA   Cooke J.E., Seguin A., Mackay J.J.;
RT   "Gene family structure, expression and functional analysis of HD-Zip III
RT   genes in angiosperm and gymnosperm forest trees.";
RL   BMC Plant Biol. 10:273-273(2010).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC   -!- SIMILARITY: Belongs to the HD-ZIP homeobox family. Class III subfamily.
CC       {ECO:0000256|ARBA:ARBA00010338}.
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DR   EMBL; HQ391915; ADV04323.1; -; mRNA.
DR   AlphaFoldDB; E7DX25; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   CDD; cd14686; bZIP; 1.
DR   CDD; cd00086; homeodomain; 1.
DR   CDD; cd08875; START_ArGLABRA2_like; 1.
DR   Gene3D; 3.30.530.20; -; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR044830; HD-Zip_III.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR013978; MEKHLA.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   InterPro; IPR002913; START_lipid-bd_dom.
DR   PANTHER; PTHR45950; HOMEOBOX-LEUCINE ZIPPER PROTEIN ATHB-14; 1.
DR   PANTHER; PTHR45950:SF7; HOMEOBOX-LEUCINE ZIPPER PROTEIN ATHB-14; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   Pfam; PF08670; MEKHLA; 1.
DR   Pfam; PF01852; START; 1.
DR   SMART; SM00389; HOX; 1.
DR   SMART; SM00234; START; 1.
DR   SUPFAM; SSF55961; Bet v1-like; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
DR   PROSITE; PS50848; START; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000256|RuleBase:RU000682};
KW   Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000256|RuleBase:RU000682};
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000256|RuleBase:RU000682}.
FT   DOMAIN          12..76
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DOMAIN          153..381
FT                   /note="START"
FT                   /evidence="ECO:0000259|PROSITE:PS50848"
FT   DNA_BIND        14..77
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   COILED          86..113
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   836 AA;  91628 MW;  4FEB1037BA3DEB26 CRC64;
     MTMTVVTAQS CGMEAGKYVR YTAEQVEALE RLYNDCPKPS SLRRQQLIRE CPILSHIEPK
     QIKVWFQNRR CREKQRKEAS RLQTVNRKLT AMNKLLMEEN DRLQKQVSQL VYENGYFRQQ
     IQTVSIATTD TSCESVVTSG PHPHHLTPQH PPRDASPAGF LSIAEETLTQ LLSKATETAV
     DWIQMPGMKP GPDSIGIVTI SNSCTGVAAR ACGFAGLEPS KVADILKDRP AWLHDCRCLN
     VLTAFPTGKG GTVEVLYTQM YAPTTLAPAR DLLTLRYTSL LEDGSLVVCE RSLTGIQSGP
     NMPSVQHFVR AQMLPSGYLI RPCEGGGCII HIVDHMDLEP WSVPEVIRPL YESSAVLATR
     VTITALRHLR QVAQEVSGEV VLGWGRQPAA LRAFSQRLCR GFNDAVNGFV DDGWSLLGSD
     GVEDVIIAIN SSPSKFLGSQ LASSDGISAL NGGILCAKAS MLLQNVPPAL LVRFLREHRS
     EWADCNVDAY SSATMKANAY NVPGSLGGIT GSQVILPLAH TVEHEEFLEV IKLEGQGLTH
     EEALLSKDMF LLQLCSGIDE HAVGFCAQLV FAPIDASFAD DAPLLPSGFR VIPLESGSDA
     SPPNRTLDLA SALEVGSAGT RASGDCGDSP YNLRSVLTIA FQFTYQNHVR DSVAAMARQY
     VRHVIASVQR VAIALAPSLQ SPHPPPGTPE ALTLARWICE SYRMHLGLEL IESSSETNES
     VLKLLWHHSD GIMCCSWKTL PVFTFANQAG LDMLETTLVA LQDISLEKIL DENGRKRLCS
     DFTQIMQQGY AYLPAGICIS SMGRPVSYDR AIAWKVLNDE DVTHCISFMF VNWSFV
//