ID   E7EKK1_9NEOB            Unreviewed;        70 AA.
AC   E7EKK1;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   03-MAY-2023, entry version 40.
DE   SubName: Full=Brevinin-1TR1 antimicrobial peptide {ECO:0000313|EMBL:ADV36201.1};
OS   Amolops torrentis.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Amolops.
OX   NCBI_TaxID=110105 {ECO:0000313|EMBL:ADV36201.1};
RN   [1] {ECO:0000313|EMBL:ADV36201.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Wang H., Liu J.;
RT   "Antimicrobial peptides from amphibian skin of Amolops torrentis.";
RL   Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the frog skin active peptide (FSAP) family.
CC       Brevinin subfamily. {ECO:0000256|ARBA:ARBA00008230}.
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DR   EMBL; HQ735178; ADV36201.1; -; mRNA.
DR   AlphaFoldDB; E7EKK1; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   InterPro; IPR012520; Antimicrobial_frog_1.
DR   InterPro; IPR004275; Frog_antimicrobial_propeptide.
DR   Pfam; PF08018; Antimicrobial_1; 1.
DR   Pfam; PF03032; FSAP_sig_propep; 1.
PE   2: Evidence at transcript level;
KW   Antimicrobial {ECO:0000256|ARBA:ARBA00022577};
KW   Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW   Cytolysis {ECO:0000256|ARBA:ARBA00022852};
KW   Fungicide {ECO:0000256|ARBA:ARBA00022577};
KW   Hemolysis {ECO:0000256|ARBA:ARBA00022735};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..70
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003217290"
FT   DOMAIN          2..45
FT                   /note="Frog antimicrobial peptide propeptide"
FT                   /evidence="ECO:0000259|Pfam:PF03032"
FT   DOMAIN          48..70
FT                   /note="Frog antimicrobial peptide brevinin-1 type"
FT                   /evidence="ECO:0000259|Pfam:PF08018"
SQ   SEQUENCE   70 AA;  8212 MW;  DF16BF49441A778D CRC64;
     MFTTKKPMLL LFFLGTINFS LCEQERDAEE ERRDDQDKRD VEVEKRFFLP LLGAAAQVLP
     SLICKIFKKC
//