ID E7F380_DANRE Unreviewed; 429 AA.
AC E7F380; A0A8M6YZA8;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Galactose-3-O-sulfotransferase 3 {ECO:0000313|Ensembl:ENSDARP00000102615, ECO:0000313|RefSeq:XP_017212448.1};
GN Name=gal3st3 {ECO:0000313|Ensembl:ENSDARP00000102615,
GN ECO:0000313|RefSeq:XP_017212448.1,
GN ECO:0000313|ZFIN:ZDB-GENE-121001-3};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000102615};
RN [1] {ECO:0000313|Ensembl:ENSDARP00000102615}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000102615};
RG Ensembl;
RL Submitted (APR-2011) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000102615, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000102615};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [3] {ECO:0000313|RefSeq:XP_017212448.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=27189481;
RA Pasquier J., Cabau C., Nguyen T., Jouanno E., Severac D., Braasch I.,
RA Journot L., Pontarotti P., Klopp C., Postlethwait J.H., Guiguen Y.,
RA Bobe J.;
RT "Gene evolution and gene expression after whole genome duplication in fish:
RT the PhyloFish database.";
RL BMC Genomics 17:368-368(2016).
RN [4] {ECO:0000313|RefSeq:XP_017212448.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the galactose-3-O-sulfotransferase family.
CC {ECO:0000256|ARBA:ARBA00008124}.
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DR EMBL; AL808019; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABZ01078177; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABZ01088234; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABZ01088235; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABZ01088236; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABZ01088237; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABZ01088238; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_017212448.1; XM_017356959.2.
DR STRING; 7955.ENSDARP00000102615; -.
DR PaxDb; 7955-ENSDARP00000102615; -.
DR Ensembl; ENSDART00000109485; ENSDARP00000102615; ENSDARG00000073728.
DR Ensembl; ENSDART00000109485.5; ENSDARP00000102615.2; ENSDARG00000073728.5.
DR GeneID; 100330824; -.
DR KEGG; dre:100330824; -.
DR AGR; ZFIN:ZDB-GENE-121001-3; -.
DR CTD; 89792; -.
DR ZFIN; ZDB-GENE-121001-3; gal3st3.
DR eggNOG; ENOG502QPNT; Eukaryota.
DR HOGENOM; CLU_040616_1_0_1; -.
DR OMA; IVTNHMR; -.
DR OrthoDB; 3032344at2759; -.
DR PhylomeDB; E7F380; -.
DR TreeFam; TF314802; -.
DR Proteomes; UP000000437; Chromosome 7.
DR Bgee; ENSDARG00000073728; Expressed in retina and 9 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0050694; F:galactose 3-O-sulfotransferase activity; IBA:GO_Central.
DR GO; GO:0001733; F:galactosylceramide sulfotransferase activity; IEA:InterPro.
DR GO; GO:0009247; P:glycolipid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR009729; Gal-3-0_sulfotransfrase.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR14647; GALACTOSE-3-O-SULFOTRANSFERASE; 1.
DR PANTHER; PTHR14647:SF83; GALACTOSE-3-O-SULFOTRANSFERASE 3; 1.
DR Pfam; PF06990; Gal-3-0_sulfotr; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..429
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041116642"
FT REGION 401..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..429
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 429 AA; 49242 MW; ACAA75ABF8A152DA CRC64;
MSQKKIFLVL IAISTVSFLL HHGGHLNLTL ETFWMGCPST TVSVNQGSSG HSGKHTSVAF
LKTHKTASST VQNILFRFAE RNNLTVALPI TSCDHQFCYP RPFSVHFVHP HTSPPDIITS
HLRFSRTELR HLMPNNTIYI TILREPGAMF ESLFSYYNQY CLSFKRVPNG SLETFLDEPW
NYYRPDEKDS MYARNTLTFD LGGDKDRPFT ELYVKRFAAE MEKVFSLVMI AEYFDESLVL
LRRLLAWDLD DVLYVSLNMR TADSKSSLSS DNTEKIRDWN AIDSALYDHF NASLWRQLRA
LGLACVEREV QLLRQSRDRL VRSCFGGSLP PLRSAAQITN KELRPWQPSA KVTIVGYDLP
VNISKKGPIP PRDECLKMIM PEVQYTKLLL RSESVRYRKR LPIRSRQQTA RSVGQPRVHK
ESSSQSLVP
//
