ID E7FC27_DANRE Unreviewed; 640 AA.
AC E7FC27; A0A8M2B4X3;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Intermediate filament family orphan 1 isoform X1 {ECO:0000313|RefSeq:XP_005157995.1};
DE SubName: Full=Intermediate filament family orphan 1b {ECO:0000313|Ensembl:ENSDARP00000083819};
GN Name=iffo1b {ECO:0000313|Ensembl:ENSDARP00000083819,
GN ECO:0000313|RefSeq:XP_005157995.1,
GN ECO:0000313|ZFIN:ZDB-GENE-050208-308};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000083819};
RN [1] {ECO:0000313|Ensembl:ENSDARP00000083819}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000083819};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000083819, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000083819};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [3] {ECO:0000313|RefSeq:XP_005157995.1}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|RefSeq:XP_005157995.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CU861451; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005157995.1; XM_005157938.4.
DR STRING; 7955.ENSDARP00000083819; -.
DR PaxDb; 7955-ENSDARP00000083819; -.
DR Ensembl; ENSDART00000089386; ENSDARP00000083819; ENSDARG00000062108.
DR Ensembl; ENSDART00000089386.6; ENSDARP00000083819.5; ENSDARG00000062108.7.
DR GeneID; 563794; -.
DR KEGG; dre:563794; -.
DR AGR; ZFIN:ZDB-GENE-050208-308; -.
DR CTD; 563794; -.
DR ZFIN; ZDB-GENE-050208-308; iffo1b.
DR eggNOG; ENOG502QRD7; Eukaryota.
DR OMA; EYTMRVE; -.
DR OrthoDB; 5318369at2759; -.
DR PhylomeDB; E7FC27; -.
DR TreeFam; TF331217; -.
DR Proteomes; UP000000437; Chromosome 16.
DR Bgee; ENSDARG00000062108; Expressed in retina and 18 other cell types or tissues.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR039008; IF_rod_dom.
DR PANTHER; PTHR14516; 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE FAMILY MEMBER; 1.
DR PANTHER; PTHR14516:SF2; NON-HOMOLOGOUS END JOINING FACTOR IFFO1; 1.
DR Pfam; PF00038; Filament; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT DOMAIN 113..614
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 208..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 608..640
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 316..364
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 558..585
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 216..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..623
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 640 AA; 71719 MW; 487A915A295CCB3A CRC64;
MPDLQRFSFP YRSMNSPLHH HHHHHQQQQH QQHQHPEGPG HPDSPSSLLP EAAIFGAPDP
SSFFLGEQPV PAGVTQSALD LTASSYLHFS PSLHWSQPPP PTAMALRNDL GSNISVLKTL
NLRFRCFLAK VHELERRNKI LELQLQQALD SNNKGGCTED GKTKEIGVQT GFIGPIAVRP
GSLSFQNTNN SAKRPTTLFM PSLTTVLKLE PNKPGDETTS DPNINRNPTI TVSLSTPTTE
PASANTNNSN NTPHVSSVGT GTSPNPPPRF LPGTIWSYNH TRKLGSGTET RVTSPGVSWV
HPDGVGVQID TITPEIRALY NVLAKIKRER DEYKRRWEEE YTMRMDMEQR MNDLQEDLQE
SEVCQDELAL KVQQLKAELV LFKGLMSNNL SELDSKIQEK AMKVDMDICR RIDITARLCD
VAQQRNCEDP IKIFKVPSPQ NAITSRARKQ ASQPANGSET DEPVSTSESD GGGAREDEVC
TPSTLQINEE MQRMLTQLRE CEFEDDCDSL AWEETEETLL LWEDFPGCTV TTDTSQGEQE
ECLEKVIKDT ECLFKSREKE YQETIDQIEL ELATAKSDMN RHLHEYMEMC SMKRGLDVQM
ETCRRLITQS GNNKSTSPIP GGGIDTNGET ERDKMEEGGR
//
