ID E7FMN6_9LACO Unreviewed; 367 AA.
AC E7FMN6;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE SubName: Full=Creatinase {ECO:0000313|EMBL:EFZ35715.1};
DE EC=3.4.13.9 {ECO:0000313|EMBL:EFZ35715.1};
GN Name=pepQ {ECO:0000313|EMBL:EFZ35715.1};
GN ORFNames=HMPREF0542_10163 {ECO:0000313|EMBL:EFZ35715.1};
OS Ligilactobacillus ruminis ATCC 25644.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Ligilactobacillus.
OX NCBI_TaxID=525362 {ECO:0000313|EMBL:EFZ35715.1, ECO:0000313|Proteomes:UP000004099};
RN [1] {ECO:0000313|EMBL:EFZ35715.1, ECO:0000313|Proteomes:UP000004099}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25644 {ECO:0000313|EMBL:EFZ35715.1,
RC ECO:0000313|Proteomes:UP000004099};
RA Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A.,
RA Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X.,
RA Perez L., Shen H., Wang Q., Watt J., Xi L., Xin Y., Zhou J., Deng J.,
RA Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A.,
RA Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B.,
RA Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M.,
RA Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N.,
RA Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W.,
RA Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J.,
RA Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L.,
RA Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M.,
RA Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G.,
RA Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M.,
RA Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L.,
RA Reid J., Worley K., Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFZ35715.1}.
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DR EMBL; ACGS02000012; EFZ35715.1; -; Genomic_DNA.
DR RefSeq; WP_003691665.1; NZ_GL833110.1.
DR AlphaFoldDB; E7FMN6; -.
DR MEROPS; M24.006; -.
DR PATRIC; fig|525362.12.peg.1836; -.
DR HOGENOM; CLU_017266_4_2_9; -.
DR Proteomes; UP000004099; Unassembled WGS sequence.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProt.
DR GO; GO:0008235; F:metalloexopeptidase activity; IEA:UniProt.
DR GO; GO:0102009; F:proline dipeptidase activity; IEA:UniProtKB-EC.
DR GO; GO:0046914; F:transition metal ion binding; IEA:UniProt.
DR CDD; cd01092; APP-like; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR001714; Pept_M24_MAP.
DR PANTHER; PTHR46112; AMINOPEPTIDASE; 1.
DR PANTHER; PTHR46112:SF10; DIPEPTIDASE YKVY-RELATED; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR PRINTS; PR00599; MAPEPTIDASE.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 4: Predicted;
KW Dipeptidase {ECO:0000313|EMBL:EFZ35715.1};
KW Hydrolase {ECO:0000313|EMBL:EFZ35715.1};
KW Protease {ECO:0000313|EMBL:EFZ35715.1}.
FT DOMAIN 4..134
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 146..348
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
SQ SEQUENCE 367 AA; 40747 MW; A4CBD491ABBA3F12 CRC64;
MSHITTVQNW LAQNNYDIAY VSDWKNVEYF SGFSSNPIER VLALFIFPDK DPFIFAPALE
VGSVKKAGWK YPVYGYLDHE DPFALIKGHI EDLGKNPKKW AIEKSNLTVA RYEAIKTQFN
EAEFVGDLSP LIEREKLIKT PDEIKKLHVA GDWADKAFEA GFAALSTKRT EQQVVAEIEY
AMMKAGIMHM SFDTIVQSGA NAADPHGAPL KDLIKPNELC LFDLGVVSEG YMSDASRTVA
FGKIDDRSKE IYDVCLEAQL AAQDAAKPGI TAAELDKVAR DVIDKAGYGQ YFIHRLGHGI
GQSDHEFPSI MEGNDLVLEP GMCFSIEPGI YVPGFSGVRI EDCVHITDTG CDPFTHTSKE
LRVIELD
//
