ID E7N7E8_9ACTO Unreviewed; 192 AA.
AC E7N7E8;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE SubName: Full=Antioxidant, AhpC/TSA family {ECO:0000313|EMBL:EFW27897.1};
DE EC=1.11.1.15 {ECO:0000313|EMBL:EFW27897.1};
DE SubName: Full=Peroxiredoxin {ECO:0000313|EMBL:QCT32301.1};
GN ORFNames=FBF36_01440 {ECO:0000313|EMBL:QCT32301.1}, HMPREF9057_00701
GN {ECO:0000313|EMBL:EFW27897.1};
OS Actinomyces sp. oral taxon 171 str. F0337.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=706439 {ECO:0000313|EMBL:EFW27897.1, ECO:0000313|Proteomes:UP000005722};
RN [1] {ECO:0000313|EMBL:EFW27897.1, ECO:0000313|Proteomes:UP000005722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0337 {ECO:0000313|EMBL:EFW27897.1,
RC ECO:0000313|Proteomes:UP000005722};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QCT32301.1, ECO:0000313|Proteomes:UP000310751}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0337 {ECO:0000313|EMBL:QCT32301.1,
RC ECO:0000313|Proteomes:UP000310751};
RA Collins A.J., Murugkar P., Chen T., Dewhirst F.E.;
RT "Saccharibacteria TM7 and host bacteria genomes.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AECW01000086; EFW27897.1; -; Genomic_DNA.
DR EMBL; CP040005; QCT32301.1; -; Genomic_DNA.
DR RefSeq; WP_009394355.1; NZ_GL637747.1.
DR AlphaFoldDB; E7N7E8; -.
DR eggNOG; COG0450; Bacteria.
DR HOGENOM; CLU_042529_21_3_11; -.
DR Proteomes; UP000005722; Unassembled WGS sequence.
DR Proteomes; UP000310751; Chromosome.
DR GO; GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
DR CDD; cd03015; PRX_Typ2cys; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR000866; AhpC/TSA.
DR InterPro; IPR024706; Peroxiredoxin_AhpC-typ.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR10681:SF121; ALKYL HYDROPEROXIDE REDUCTASE C; 1.
DR PANTHER; PTHR10681; THIOREDOXIN PEROXIDASE; 1.
DR Pfam; PF00578; AhpC-TSA; 1.
DR PIRSF; PIRSF000239; AHPC; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EFW27897.1}; Peroxidase {ECO:0000313|EMBL:EFW27897.1}.
FT DOMAIN 4..170
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT ACT_SITE 61
FT /note="Cysteine sulfenic acid (-SOH) intermediate; for
FT peroxidase activity"
FT /evidence="ECO:0000256|PIRSR:PIRSR000239-1"
SQ SEQUENCE 192 AA; 21317 MW; 8AAC22FB1982D433 CRC64;
MAVLTIGDQF PAYELTAVVP GNLKEVEASK PEDYFTTVSS QVPAGTWRVV FFWPKDFTFV
CPTEIAAFGD LYQDFKDRDC EVVGVSVDNE YTHYAWRRSH DKLQDLPFPM ASDLNRELTE
ALGIKRATGE ADRATFIIDP HNVIQSVSVT ADSVGRNTEE VLRQLDALQS DELCACNWQA
GAATIDALGE MS
//
