ID E7ND90_9ACTO Unreviewed; 265 AA.
AC E7ND90;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=TipAS antibiotic-recognition domain protein {ECO:0000313|EMBL:EFW25855.1};
GN ORFNames=HMPREF9057_02772 {ECO:0000313|EMBL:EFW25855.1};
OS Actinomyces sp. oral taxon 171 str. F0337.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=706439 {ECO:0000313|EMBL:EFW25855.1, ECO:0000313|Proteomes:UP000005722};
RN [1] {ECO:0000313|EMBL:EFW25855.1, ECO:0000313|Proteomes:UP000005722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0337 {ECO:0000313|EMBL:EFW25855.1,
RC ECO:0000313|Proteomes:UP000005722};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFW25855.1}.
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DR EMBL; AECW01000508; EFW25855.1; -; Genomic_DNA.
DR AlphaFoldDB; E7ND90; -.
DR eggNOG; COG0789; Bacteria.
DR HOGENOM; CLU_060077_0_6_11; -.
DR Proteomes; UP000005722; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd01106; HTH_TipAL-Mta; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 1.10.490.50; Antibiotic binding domain of TipA-like multidrug resistance regulators; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR036244; TipA-like_antibiotic-bd.
DR InterPro; IPR012925; TipAS_dom.
DR PANTHER; PTHR30204:SF90; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR TIPA; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF13411; MerR_1; 1.
DR Pfam; PF07739; TipAS; 1.
DR PRINTS; PR00040; HTHMERR.
DR SMART; SM00422; HTH_MERR; 1.
DR SUPFAM; SSF89082; Antibiotic binding domain of TipA-like multidrug resistance regulators; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS00552; HTH_MERR_1; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 7..76
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
SQ SEQUENCE 265 AA; 29913 MW; 1ABB6C173CFFBD38 CRC64;
MDFSETTMTV GEVSTLLGVS VRALHHWDES GLVHPSRRSD AGYRLYCETD IMRIQQVLVY
RQTGMSLADI KEVLDEPGAD AVTHLRRQRE LLQGQVSHLQ QMLLSIDTIL DMQQLGGRLS
LAETVEIWGT DWDPVYLAEA QAKWGDTEEW AESARRKARM TRADWEQAHS ETVALETALA
EAMHSGVEPG SPEANALARW HRKDLNRWFE VSTSKQVVIA RSYVADERYA RYYDKRAPGL
AAWVKDVIDA GARSEGVEPA TATWE
//
