ID E7NXZ0_TREPH Unreviewed; 703 AA.
AC E7NXZ0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=HAMP domain protein {ECO:0000313|EMBL:EFW36554.1};
GN ORFNames=HMPREF9554_02960 {ECO:0000313|EMBL:EFW36554.1};
OS Treponema phagedenis F0421.
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC Treponema.
OX NCBI_TaxID=754027 {ECO:0000313|EMBL:EFW36554.1, ECO:0000313|Proteomes:UP000004157};
RN [1] {ECO:0000313|EMBL:EFW36554.1, ECO:0000313|Proteomes:UP000004157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0421 {ECO:0000313|EMBL:EFW36554.1,
RC ECO:0000313|Proteomes:UP000004157};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFW36554.1}.
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DR EMBL; AEFH01000250; EFW36554.1; -; Genomic_DNA.
DR RefSeq; WP_002701171.1; NZ_GL638118.1.
DR AlphaFoldDB; E7NXZ0; -.
DR STRING; 162.TPHV1_500001; -.
DR eggNOG; COG0840; Bacteria.
DR HOGENOM; CLU_000445_107_19_12; -.
DR Proteomes; UP000004157; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 316..370
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 417..639
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 703 AA; 76949 MW; 10D6B8D050CF808A CRC64;
MGRAEKRKHS ITIKLVFYFG IVLLFSIALI SAVFLLTSYK ALTDNVTERL TLQAYNLSEI
VNVNLQSLYR QLETIARNET VRDPNFNVSE KAHSLRYEAV KNTKNFITKL FILDTSGKGF
QTDGTAVNHS GKIGVTTVLN GGMFISQPEP SAAGGFVSMY YYIPVYNVSQ KIINILVAEI
NAAMLSRDIK NASIGKTGEA FIVGTDGTII AGKDEQIVKE KLNVLEKAKQ DNAYKDFDRF
IQQALQYYGY NYDTYDFAGK KISGAFSKIS TTGWTLVICA PTEEFMGGVH KFMISVCVVI
IITIVCAGFV ILVIAYQIAK PLQKTAMALK NISQGEGDLT ISLPVRGNDE ISDIALYFNE
TIKKIRNSIA TVTYNIDKME AIGSELTEHA SKTELAAKKI EESIGNVKND VLSQTTGITE
VASVMEQSVR TVEQLNKHIA TQAASVEQSS ASIEQMVTNI RAVTDILEEN TETVESLNES
TDIGHTSLMH SVEITKMIIE RSDGLLEAST IIQNIASQTN LLAMNAAIEA AHAGNEGKGF
AVVAAEIRKL AEEAARQSKS ITMVLKELKA MIGELGKSSD TVQSVFSDIY QFAETVKTQE
DVIMKTMQMQ SAGGMEILRA IKSINTATTE VEHGATEMLT GSKETSTEMQ KLASIAAMIT
ENMNTMNTDT IKINSAIIGI AEISRKTHQS IESLAEEVKK FKI
//
