ID E7S138_9BURK Unreviewed; 608 AA.
AC E7S138;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Creatinase {ECO:0000313|EMBL:EFV93694.1};
GN ORFNames=HMPREF0551_2590 {ECO:0000313|EMBL:EFV93694.1};
OS Lautropia mirabilis ATCC 51599.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Lautropia.
OX NCBI_TaxID=887898 {ECO:0000313|EMBL:EFV93694.1, ECO:0000313|Proteomes:UP000011021};
RN [1] {ECO:0000313|EMBL:EFV93694.1, ECO:0000313|Proteomes:UP000011021}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51599 {ECO:0000313|EMBL:EFV93694.1,
RC ECO:0000313|Proteomes:UP000011021};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFV93694.1}.
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DR EMBL; AEQP01000024; EFV93694.1; -; Genomic_DNA.
DR RefSeq; WP_005675065.1; NZ_GL636062.1.
DR AlphaFoldDB; E7S138; -.
DR STRING; 887898.HMPREF0551_2590; -.
DR eggNOG; COG0006; Bacteria.
DR HOGENOM; CLU_011781_2_1_4; -.
DR Proteomes; UP000011021; Unassembled WGS sequence.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000011021}.
FT DOMAIN 16..137
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 318..531
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 545..605
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 608 AA; 65601 MW; B46955C2B161B585 CRC64;
MNAVSSSSAL QGPVQRLAAL RQTMQKQGID AWIIPSADPH LSEYLPEHWQ GRRWVSGFTG
SVGTLVVTAA TADLWADSRY WEQATAQLAG TGIQLQKLGR GRTHVEALAE ALGQGAVVGV
APDMLSRAAK RQLEQAFVAK GIQLRADGDL LAGIWTERPA LPAEPVVVHA AEFVSESAAE
KLARVRAAMQ EKGAAHHLIS SLDDIAWLTN LRGNDVSYNP VFLAHLLIGA SSATLYVDDS
RLTEPAREAL AAAGISVAPY EKAADDIARL SDSLLVDPAK VAASTLQSLK GTVPVIESVN
PSTLFKSVKS PADVAHTREA MIEDGVALCH FFADFETRLA RGEVLNELDI DRMLLEFRSQ
RPNFVSPSFG TIAGFNANAA LPHYSATPEA FSEIRGDGLL LIDSGGQYLN GTTDITRVVP
VGTPSAAHKR DNTLVLKAHI ALAETIFPEG IAGPLLDAIC RKPMWQQQCD YGHGTGHGVG
YFMNVHEGPQ VISWHAPVLP QGALKVGMIT SIEPGIYRPG KWGIRIENLV VNQPVANPKE
TEFGQFLHFE PLTLCPIDTR LMDTALMTPT EIQWVNAYHA LVREKLAPRL QGAALAWLEA
RTQPLAKS
//
