ID E7S8N2_9STRE Unreviewed; 250 AA.
AC E7S8N2;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=LytTr DNA-binding domain protein {ECO:0000313|EMBL:EFW00041.1};
GN Name=comE {ECO:0000313|EMBL:EFW00041.1};
GN ORFNames=HMPREF9421_0418 {ECO:0000313|EMBL:EFW00041.1};
OS Streptococcus australis ATCC 700641.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=888833 {ECO:0000313|EMBL:EFW00041.1, ECO:0000313|Proteomes:UP000002814};
RN [1] {ECO:0000313|EMBL:EFW00041.1, ECO:0000313|Proteomes:UP000002814}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700641 {ECO:0000313|EMBL:EFW00041.1,
RC ECO:0000313|Proteomes:UP000002814};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for high-level post-exponential phase expression of
CC a series of secreted proteins. {ECO:0000256|ARBA:ARBA00037164}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFW00041.1}.
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DR EMBL; AEQR01000004; EFW00041.1; -; Genomic_DNA.
DR RefSeq; WP_006595334.1; NZ_GL636091.1.
DR AlphaFoldDB; E7S8N2; -.
DR PATRIC; fig|888833.12.peg.1748; -.
DR eggNOG; COG3279; Bacteria.
DR HOGENOM; CLU_000445_14_6_9; -.
DR Proteomes; UP000002814; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR CDD; cd17533; REC_LytTR_AgrA-like; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 2.40.50.1020; LytTr DNA-binding domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR046947; LytR-like.
DR InterPro; IPR007492; LytTR_DNA-bd_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR37299:SF3; STAGE 0 SPORULATION PROTEIN A HOMOLOG; 1.
DR PANTHER; PTHR37299; TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR Pfam; PF04397; LytTR; 1.
DR SMART; SM00850; LytTR; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR PROSITE; PS50930; HTH_LYTTR; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000313|EMBL:EFW00041.1};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW Reference proteome {ECO:0000313|Proteomes:UP000002814}.
FT DOMAIN 2..125
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 151..245
FT /note="HTH LytTR-type"
FT /evidence="ECO:0000259|PROSITE:PS50930"
FT MOD_RES 58
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 250 AA; 29467 MW; 174D288F9021904B CRC64;
MNIVLLEDEI SQQVRVEKHV KAIAEEEGLR LNIVSTSKIT ELKEYLTNGD FHQLFFLDID
IKGDEKAGIK AAQMIREVNP FAIIAFITTK SEFATITYRY KVSALEFIEK TLNENLFKEK
IRECILYLKK NVIENKNIID FFEYSFKNME IRVPYRDILY IETTGVSHKL RLVGKNFQKE
FLGTIKDILE KDVDNHFFSP NQSYLVNQRM IVNFDRRKRL LMLEEETTCP VSRTQVKRVE
ELLNKIQKKA
//
