ID E7VD65_SALMO Unreviewed; 164 AA.
AC E7VD65;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Gluconokinase {ECO:0000256|ARBA:ARBA00012054, ECO:0000256|RuleBase:RU363066};
DE EC=2.7.1.12 {ECO:0000256|ARBA:ARBA00012054, ECO:0000256|RuleBase:RU363066};
DE Flags: Fragment;
GN Name=gntK {ECO:0000313|EMBL:AEK67801.1};
OS Salmonella enterica subsp. enterica serovar Montevideo str. 315996572.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=745015 {ECO:0000313|EMBL:AEK67801.1};
RN [1] {ECO:0000313|EMBL:AEK67801.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=315996572 {ECO:0000313|EMBL:AEK67801.1};
RX PubMed=21345093; DOI=10.1056/NEJMc1100443;
RA Lienau E.K., Strain E., Wang C., Zheng J., Ottesen A.R., Keys C.E.,
RA Hammack T.S., Musser S.M., Brown E.W., Allard M.W., Cao G., Meng J.,
RA Stones R.;
RT "Identification of a salmonellosis outbreak by means of molecular
RT sequencing.";
RL N. Engl. J. Med. 364:981-982(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-gluconate = 6-phospho-D-gluconate + ADP + H(+);
CC Xref=Rhea:RHEA:19433, ChEBI:CHEBI:15378, ChEBI:CHEBI:18391,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58759, ChEBI:CHEBI:456216;
CC EC=2.7.1.12; Evidence={ECO:0000256|ARBA:ARBA00001329,
CC ECO:0000256|RuleBase:RU363066};
CC -!- PATHWAY: Carbohydrate acid metabolism; D-gluconate degradation.
CC {ECO:0000256|ARBA:ARBA00004875}.
CC -!- SIMILARITY: Belongs to the gluconokinase GntK/GntV family.
CC {ECO:0000256|ARBA:ARBA00008420, ECO:0000256|RuleBase:RU363066}.
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DR EMBL; JF711225; AEK67801.1; -; Genomic_DNA.
DR AlphaFoldDB; E7VD65; -.
DR PATRIC; fig|745015.3.peg.3429; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046316; F:gluconokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd02021; GntK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR031322; Shikimate/glucono_kinase.
DR InterPro; IPR006001; Therm_gnt_kin.
DR NCBIfam; TIGR01313; therm_gnt_kin; 1.
DR PANTHER; PTHR43442; GLUCONOKINASE-RELATED; 1.
DR PANTHER; PTHR43442:SF3; GLUCONOKINASE-RELATED; 1.
DR Pfam; PF01202; SKI; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363066};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU363066};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363066};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363066}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AEK67801.1"
SQ SEQUENCE 164 AA; 18111 MW; 606D922D15EE0A8A CRC64;
MGVSGSGKSA VASAVAHQLH AAFLDGDFLH PRCNIEKMAS GEPLNDDDRK PWLQALNDAA
FAMQRTNKIS LIVCSALKKH YRDLLREGNP NLSFIYLKGD FDVIESRLKA RKGHFFKTQM
LVTQFETLQE PGADERDVLV VDIDQPLEGV VASTIEVINK GSTL
//
