ID E8LU48_9VIBR Unreviewed; 445 AA.
AC E8LU48;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN ORFNames=VIBR0546_21550 {ECO:0000313|EMBL:EGA65713.1};
OS Vibrio brasiliensis LMG 20546.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio; Vibrio oreintalis group.
OX NCBI_TaxID=945543 {ECO:0000313|EMBL:EGA65713.1, ECO:0000313|Proteomes:UP000004371};
RN [1] {ECO:0000313|EMBL:EGA65713.1, ECO:0000313|Proteomes:UP000004371}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 20546 {ECO:0000313|EMBL:EGA65713.1,
RC ECO:0000313|Proteomes:UP000004371};
RX PubMed=21930677; DOI=10.1099/ijs.0.032375-0;
RA Hoffmann M., Monday S.R., Allard M.W., Strain E.A., Whittaker P., Naum M.,
RA McCarthy P.J., Lopez J.V., Fischer M., Brown E.W.;
RT "Vibrio caribbeanicus sp. nov., isolated from the marine sponge
RT Scleritoderma cyanea.";
RL Int. J. Syst. Evol. Microbiol. 62:1736-1743(2012).
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGA65713.1}.
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DR EMBL; AEVS01000062; EGA65713.1; -; Genomic_DNA.
DR RefSeq; WP_006879359.1; NZ_AEVS01000062.1.
DR AlphaFoldDB; E8LU48; -.
DR STRING; 945543.VIBR0546_21550; -.
DR eggNOG; COG1345; Bacteria.
DR OrthoDB; 9810816at2; -.
DR Proteomes; UP000004371; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:EGA65713.1};
KW Cilium {ECO:0000313|EMBL:EGA65713.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Flagellum {ECO:0000313|EMBL:EGA65713.1};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 2..100
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 216..439
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 445 AA; 48217 MW; ADB7645331813E0A CRC64;
MSSIDPATMA TQLATFDVQS FRQRYSTQAS QYQSQLDALG KVESALREFR TAVTEMNSST
AGIIKNSATI SQDGFFTANA SSTALTGSYQ IFVEQVATAH QVSANMPADL DSTTEVPITG
SLDLTIDGNT LTIDLSTLDS DGDGKATIAD LTSAINNDPN NPGVNATLVR SNGQTHFMLA
SEETGVANTI NVSASGTGQA WFEDAFTTLN QISTPQDAVI WLGAKDTGLK LTGSSNTFSN
AIDGVDITVT KAQASGEAPL SMTIGGDQEA TKEQVNQFID AYNNLMSVID QYSKVNGEDL
QRPALASDPT LRSIEGQMKS LVRGDFGGLR LNDIGIEIDR DGKMKIDSER FEQAQLNNST
GLEAMFNGDG NLLDSVEDLI EPYLQFSSGL FKSRKDALQE NINRINDKQV VLDRKYDMAY
DRYLKQFTQM NSIMRQMNQT MSLFG
//
