ID E8QU33_HELPW Unreviewed; 565 AA.
AC E8QU33;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Chemotaxis protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=HPSA_00535 {ECO:0000313|EMBL:ADU84131.1};
OS Helicobacter pylori (strain SouthAfrica7).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=907239 {ECO:0000313|EMBL:ADU84131.1, ECO:0000313|Proteomes:UP000007467};
RN [1] {ECO:0000313|Proteomes:UP000007467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SouthAfrica7 {ECO:0000313|Proteomes:UP000007467};
RA Kersulyte D., Segal I., Mistry R., Berg D.E.;
RT "Genome sequence of Helicobacter pylori strain SouthAfrica7.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADU84131.1, ECO:0000313|Proteomes:UP000007467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SouthAfrica7 {ECO:0000313|EMBL:ADU84131.1,
RC ECO:0000313|Proteomes:UP000007467};
RX PubMed=24072860;
RA Duncan S.S., Bertoli M.T., Kersulyte D., Valk P.L., Tamma S., Segal I.,
RA McClain M.S., Cover T.L., Berg D.E.;
RT "Genome Sequences of Three hpAfrica2 Strains of Helicobacter pylori.";
RL Genome Announc. 1:e00729-13(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; CP002336; ADU84131.1; -; Genomic_DNA.
DR RefSeq; WP_000230722.1; NC_017361.1.
DR AlphaFoldDB; E8QU33; -.
DR KEGG; hes:HPSA_00535; -.
DR PATRIC; fig|907239.3.peg.103; -.
DR eggNOG; COG0840; Bacteria.
DR HOGENOM; CLU_000445_107_21_7; -.
DR OrthoDB; 9776024at2; -.
DR Proteomes; UP000007467; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR033480; sCache_2.
DR PANTHER; PTHR32089:SF112; HEME-BASED AEROTACTIC TRANSDUCER HEMAT; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR Pfam; PF17200; sCache_2; 1.
DR SMART; SM01049; Cache_2; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 212..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 233..288
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 286..550
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 565 AA; 62746 MW; 7C44BBDC7E6A6C4E CRC64;
MVFASIFSSL GARIVLVVLA ALLGLGGLSI SLVKVMQKDA LEQLMGHLET GQYKKREKTL
AYMTRLLEQG IHEYYKNFDN ATARKMALDY FKRINDDKGM IYMVVVDKNG VVLFDPVNPK
TIGQSGLNLQ SVDGVYYVKG YLEAAKKGGG YTYYKMPKYD GGVPEKKFAY SHYDEVSQMV
IAATSYYTDI NAENQAIRQG VEKVFNENTT KLFLWILTAT IALVVLTLIY AKLRIVKRID
DLVLKINAFS HGDKDLRAKI EVDDRNDEIS QVGHGVNLFV EKARLIMEEI KGISTFNKTS
MDKLVQITKE TQESMKNSST TLNSVKDKAT DVASVMNASI EQSQGLRKRL IETQGLVKES
KNAIGDLFSQ IIEGAHTEEE LSNKVEQLSR NADDVKSILD IINDIADQTN LLALNAAIEA
ARAGEHGRGF AVVADEVRNL AGRTQKSLAE INSTIMVIVQ EINDVSSQMN LNSQKMERLS
DMSKGVQETY EKMSANLSSV VLDSNQSMDD YAKSGHQIEA MVSDFIEVEK VASKTLADSS
DILKIATHVS ETTKNLDKQV NLFKT
//
