ID E8R0B0_ISOPI Unreviewed; 332 AA.
AC E8R0B0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Metallophosphoesterase {ECO:0000313|EMBL:ADV62237.1};
GN OrderedLocusNames=Isop_1653 {ECO:0000313|EMBL:ADV62237.1};
OS Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B).
OC Bacteria; Planctomycetota; Planctomycetia; Isosphaerales; Isosphaeraceae;
OC Isosphaera.
OX NCBI_TaxID=575540 {ECO:0000313|EMBL:ADV62237.1, ECO:0000313|Proteomes:UP000008631};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 43644;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Saunders E., Brettin T.,
RA Detter J.C., Han C., Tapia R., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Eisen J.A.;
RT "The complete sequence of chromosome of Isophaera pallida ATCC 43644.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADV62237.1, ECO:0000313|Proteomes:UP000008631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43644 / DSM 9630 / IS1B
RC {ECO:0000313|Proteomes:UP000008631};
RX PubMed=21475588; DOI=10.4056/sigs.1533840;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Goker M., Cleland D., Saunders E., Lapidus A., Nolan M., Lucas S.,
RA Hammon N., Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L.,
RA Pitluck S., Liolios K., Pagani I., Ivanova N., Mavromatis K., Pati A.,
RA Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Detter J.C., Beck B., Woyke T., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Isosphaera pallida type strain (IS1B).";
RL Stand. Genomic Sci. 4:63-71(2011).
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DR EMBL; CP002353; ADV62237.1; -; Genomic_DNA.
DR AlphaFoldDB; E8R0B0; -.
DR KEGG; ipa:Isop_1653; -.
DR eggNOG; COG1408; Bacteria.
DR HOGENOM; CLU_025443_3_2_0; -.
DR InParanoid; E8R0B0; -.
DR Proteomes; UP000008631; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR PANTHER; PTHR31302:SF0; TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN; 1.
DR PANTHER; PTHR31302; TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN-RELATED; 1.
DR Pfam; PF00149; Metallophos; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008631};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 50..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 93..258
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 332 AA; 37163 MW; CD39D869CCCEF1B3 CRC64;
MITTPYDPPP SSRSPSPSIG EKHSGKGVNR GVPAVLNCNR IKRRRFLKHS VAALGAGLAG
CLGWTFWIEP FWVEIVERPL PLRNLPDHWV GKTVVQISDL HVCNLLDLDF MRRSLASIAE
LDPELVVITG DFMTCERDEW IDTTARVMES LRPGRAGILA VPGNHDYGAA WDRPEVAECL
GQRLGDLGIR LLRNQVVNVN DLQIIGLDDL WSGCLDAAKV WPRVDPNRAS LVLCHNPDAA
DLPIWSGYQG WILAGHTHGG QCKPPFLPPP LLPVRNRRYT SGAFDLYDGR WLYINRALGY
LRQVRFNVRP EITRFILVRD ATPAKPSRRP LG
//
