ID E8T7X5_MESCW Unreviewed; 542 AA.
AC E8T7X5;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:ADV14086.1};
GN OrderedLocusNames=Mesci_4985 {ECO:0000313|EMBL:ADV14086.1};
OS Mesorhizobium ciceri biovar biserrulae (strain HAMBI 2942 / LMG 23838 /
OS WSM1271).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Phyllobacteriaceae; Mesorhizobium.
OX NCBI_TaxID=765698 {ECO:0000313|EMBL:ADV14086.1, ECO:0000313|Proteomes:UP000007471};
RN [1] {ECO:0000313|Proteomes:UP000007471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HAMBI 2942 / LMG 23838 / WSM1271
RC {ECO:0000313|Proteomes:UP000007471};
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Nandasena K., Reeve W.G., Howieson J.G., O'Hara G.,
RA Tiwari R.P., Woyke T.;
RT "Complete sequence of chromosome of Mesorhizobium ciceri bv. biserrulae
RT WSM1271.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; CP002447; ADV14086.1; -; Genomic_DNA.
DR RefSeq; WP_013532739.1; NC_014923.1.
DR RefSeq; YP_004144136.1; NC_014923.1.
DR AlphaFoldDB; E8T7X5; -.
DR STRING; 765698.Mesci_4985; -.
DR KEGG; mci:Mesci_4985; -.
DR PATRIC; fig|765698.3.peg.5500; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_5_5; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000007471; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd12119; ttLC_FACS_AlkK_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43859; ACYL-ACTIVATING ENZYME; 1.
DR PANTHER; PTHR43859:SF67; MEDIUM-CHAIN-FATTY-ACID--COA LIGASE (ALKK-3); 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:ADV14086.1}.
FT DOMAIN 18..400
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 450..524
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 542 AA; 59919 MW; 8B2569B6DECC0EBF CRC64;
MLGLMQEWPL LCHKLIDNAE RQHGMREIVS RSIEGPIVRT TYADIHRRAL KVAQRLERDG
YGLGDRIATL AWNTARHIEA WYGIMGIGAI YHTLNPRLFP EQIVWIMNHA EDKAVFVDLT
FVPLLEKIAG AVKSLKQVIV LTDKAHMPQT TLPNVVAYEE WLDEADGDFA WKTFDESTAA
GMCYTSGTTG DPKGVVYSHR SNVLHAMIAA MPDAMGLSSR DTILPVVPMF HANAWGLGQS
GPMIGAKLVM PGCKMDGASI YELLDTEKVT FSAAVPTVWM MLLQHLEETG KKLPYLNKVV
IGGSSCPRAT MTKFQQNYDV QVIHAWGMTE MSPLGTLCTL KPDYAGLEGE ARLDVQQKQG
YPPFGVEMKV TDDDNNAQPW DGKTFGRLKV RGPAVARAYY GGAGVEQFDG DGWFDTGDVA
HIDAGGYMQI TDRAKDVIKS GGEWISTIDL ENLAVGHPDV AEAAAIGVHH SKWGERPLLV
VVRKPGKEPS KADILDFMDG KVAKWWMPDD VAFVGEIPHT ATGKIQKITL RQQFKDYRLP
TD
//
