ID   E8TE33_MESCW            Unreviewed;       808 AA.
AC   E8TE33;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 59.
DE   SubName: Full=FAD dependent oxidoreductase {ECO:0000313|EMBL:ADV12205.1};
GN   OrderedLocusNames=Mesci_3080 {ECO:0000313|EMBL:ADV12205.1};
OS   Mesorhizobium ciceri biovar biserrulae (strain HAMBI 2942 / LMG 23838 /
OS   WSM1271).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Phyllobacteriaceae; Mesorhizobium.
OX   NCBI_TaxID=765698 {ECO:0000313|EMBL:ADV12205.1, ECO:0000313|Proteomes:UP000007471};
RN   [1] {ECO:0000313|Proteomes:UP000007471}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HAMBI 2942 / LMG 23838 / WSM1271
RC   {ECO:0000313|Proteomes:UP000007471};
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA   Ivanova N., Nandasena K., Reeve W.G., Howieson J.G., O'Hara G.,
RA   Tiwari R.P., Woyke T.;
RT   "Complete sequence of chromosome of Mesorhizobium ciceri bv. biserrulae
RT   WSM1271.";
RL   Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
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DR   EMBL; CP002447; ADV12205.1; -; Genomic_DNA.
DR   RefSeq; WP_013530888.1; NC_014923.1.
DR   RefSeq; YP_004142255.1; NC_014923.1.
DR   AlphaFoldDB; E8TE33; -.
DR   STRING; 765698.Mesci_3080; -.
DR   KEGG; mci:Mesci_3080; -.
DR   PATRIC; fig|765698.3.peg.3570; -.
DR   eggNOG; COG0404; Bacteria.
DR   eggNOG; COG0665; Bacteria.
DR   HOGENOM; CLU_007884_11_1_5; -.
DR   OrthoDB; 9804379at2; -.
DR   Proteomes; UP000007471; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
FT   DOMAIN          6..367
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          371..424
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          427..695
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          722..800
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   808 AA;  88310 MW;  83126315A66523B2 CRC64;
     MKSHAKVVVI GGGVVGCSVL FHLARHGWTD VVLLERDELT SGSTWHAAGG MHTINGDPNV
     AKLQKYTINL YKEIEELSGQ ATGVHLTGGV LLAATEARLD WLRGVVAKGR YLGIELEEIS
     PNEAAELMPL LDPKQFVGAV RNKEDGHLDP SGVTHAYAKA ARKLGAEVER FTKVEDIVRR
     PDGLWRVITN KGEVVAEHVV NAGGLWAREV GRMVGLELPV LAMEHMYLIT EDMPEVAAWN
     AKTGTEIIHA VDFDGELYLR QERGGMLMGT YEKANKPWSE YQTPWNFGHE LLAPDIDRIA
     PSLEVGFRHF PAFQNTGIKQ IINGPFTFAP DGNPLVGPVR GLPGFWVACG VMAGFSQGGG
     VGLALSNWMI EGDPGADIWA MDVARYGDWA TMAYTNAKVR ENYSRRFSIR FPNEELPAGR
     PLKTTPVYDL LSAKGAQWGV AYGLEVPLWY APEGVKDEFS WRRSSDFTQV AKEVATVRDG
     VGLSEISSFA KYKVTGEGAA AWLDRMLACK LPKPDRMTLA PMLKEDGRLI GDFTLANLGS
     EGWFLAGSGI AEQYHMRWFE KHLPDDGSVR IEALGAKLTG LSIAGPKARD VLAKATRSDV
     SNAAFSFMAI GRMDIGMAPC LVGRVSYTGD LGYEIWVAPE YQRAAYQALM AAGGEFGIGL
     FGSRALNALR LDKNYGSWGR EYRPIYGPLE AGLDRFVAYG KDADFIGKAA ALAELRQGGK
     LRLRAFIVDA DDADVIGDEP IWFDGAVRGW VTSGGYAHHS KKSVAVGYVP KEIADESDGF
     EIELLGKRHA ARIQAVPLFD ANFERMRA
//