ID   E8TG33_MESCW            Unreviewed;       803 AA.
AC   E8TG33;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=FAD dependent oxidoreductase {ECO:0000313|EMBL:ADV12303.1};
GN   OrderedLocusNames=Mesci_3179 {ECO:0000313|EMBL:ADV12303.1};
OS   Mesorhizobium ciceri biovar biserrulae (strain HAMBI 2942 / LMG 23838 /
OS   WSM1271).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Phyllobacteriaceae; Mesorhizobium.
OX   NCBI_TaxID=765698 {ECO:0000313|EMBL:ADV12303.1, ECO:0000313|Proteomes:UP000007471};
RN   [1] {ECO:0000313|Proteomes:UP000007471}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HAMBI 2942 / LMG 23838 / WSM1271
RC   {ECO:0000313|Proteomes:UP000007471};
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA   Ivanova N., Nandasena K., Reeve W.G., Howieson J.G., O'Hara G.,
RA   Tiwari R.P., Woyke T.;
RT   "Complete sequence of chromosome of Mesorhizobium ciceri bv. biserrulae
RT   WSM1271.";
RL   Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
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DR   EMBL; CP002447; ADV12303.1; -; Genomic_DNA.
DR   RefSeq; WP_013530986.1; NC_014923.1.
DR   RefSeq; YP_004142353.1; NC_014923.1.
DR   AlphaFoldDB; E8TG33; -.
DR   STRING; 765698.Mesci_3179; -.
DR   KEGG; mci:Mesci_3179; -.
DR   PATRIC; fig|765698.3.peg.3675; -.
DR   eggNOG; COG0404; Bacteria.
DR   eggNOG; COG0665; Bacteria.
DR   HOGENOM; CLU_007884_11_1_5; -.
DR   OrthoDB; 9804379at2; -.
DR   Proteomes; UP000007471; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
FT   DOMAIN          7..365
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          369..422
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          426..691
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          718..795
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   803 AA;  87367 MW;  C782CE580421199F CRC64;
     MKSHYRAVVI GGGVVGASVL YHLTRFGWSD VALIERAELT AGSTWHAAAG FHALNADPNV
     AALQDYTINL YREIEAESGW DIGLHMTGGV NIASDPARWE WLKSAWAVFQ SVGIETARLV
     TPDEIKAICP IVDVTGVLGG LHDSNEGHLD PYGTTHAYAG AAKKRGADII LRNRVVELKA
     RADGRWDVIT EQGTIIAEHV VNAGGLWAKQ LGRMAGVDLP VTPMEHHYFI TDDIPEIAAL
     DREIGIAVDL DGFSYLRQER KGVLLGVYEQ NPKHWNMDGA PWDYGIELIP EDIDRISPEL
     AKAHERFPCL ATAGIRKWVN GAFTFTPDGN PIVGPVRGLK NYWVACGVMA GFSQGGGVGK
     SLAEWMIFGE PQADIFGMDI ARYGAFAANR EYLRQTTRQF YSRRFVMTFP NERLPAGRPL
     KRPGAYDGMS AAGCEWTASW GLEIPAYFAP MGFAENTTLR RSNAFDIVGE EALQVRRAAG
     LVDISAYARY AVSGLGAEAW LDRLLACRLP KPGRAGLAPM LGHDGRLKGD LTVFNWGGGS
     YWLMGSYYLR EFHMRWFESH AAEGVTIADL SDTMSGFLLT GPNAREILER TTHQDVSSAA
     LPFMACGAFD IGMVQARVAR LSIAGELGFE ISCPVTMHAT LRDTLLAAGE DLGLAEIGYY
     ALNALRLEKS FGIWSREFTQ GHTPGQTGLD RFIAFGKSDF IGREAALKQR EAGSGQCLVT
     LEIDALDADA SGFEPVWHQG RRVGFVTSGG YGYTVGKSLA LALVDRDFAG EGTALSVHVV
     GEERPARVVA ASPYDPLGKA MRQ
//