ID E8UVK7_THEBF Unreviewed; 625 AA.
AC E8UVK7;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 63.
DE SubName: Full=PAS sensor protein {ECO:0000313|EMBL:ADV80259.1};
GN OrderedLocusNames=Thebr_1720 {ECO:0000313|EMBL:ADV80259.1};
OS Thermoanaerobacter brockii subsp. finnii (strain ATCC 43586 / DSM 3389 /
OS AKO-1) (Thermoanaerobacter finnii).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermoanaerobacter.
OX NCBI_TaxID=509193 {ECO:0000313|EMBL:ADV80259.1, ECO:0000313|Proteomes:UP000002062};
RN [1] {ECO:0000313|EMBL:ADV80259.1, ECO:0000313|Proteomes:UP000002062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43586 / DSM 3389 / AKO-1
RC {ECO:0000313|Proteomes:UP000002062};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Chertkov O., Munk C., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Hemme C.L., Woyke T.;
RT "Complete sequence of Thermoanaerobacter brockii finnii Ako-1.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002466; ADV80259.1; -; Genomic_DNA.
DR RefSeq; WP_012269552.1; NC_014964.1.
DR AlphaFoldDB; E8UVK7; -.
DR KEGG; tbo:Thebr_1720; -.
DR HOGENOM; CLU_000445_8_5_9; -.
DR Proteomes; UP000002062; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 3.40.50.10660; PrpR receptor domain-like; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR010524; Sig_transdc_resp-reg_PrpR_N.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR32071:SF57; SIGMA L-DEPENDENT TRANSCRIPTIONAL REGULATOR YQIR-RELATED; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF06506; PrpR_N; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF159800; PrpR receptor domain-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 190..245
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 319..549
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 625 AA; 69695 MW; 1538B1BD28CD6DA5 CRC64;
MKIVLIAPYR DLLETAITVK KDLNVDIELE LGDLSEGVKV AREWEKKGVD IIISRGGTYQ
LIKESVSVPV VEIKVSAFDI LRQFNGLIGC KEIIGVAGYK NVIYGCEVIG EILDLNLIKV
VIEKEEEGLR QVAAAKEKGV SLIIGDTIGA YSAKRLGLKS RLITSGKEAV AAAVSESFRL
AQALKAEKEK AEQIRTIVDF VHDGIIAIDK EGRVSIYNRM AEKIFKRPPA EAVGRKVETV
VPNTRLYEVI ETGKPQIGEL QEVLGTMITT NRVPIVVGNE VVGAVATFQD VTMLQKVEQK
IRRQLADRGL VAMYTFDDII YSSEKMKDVV NQAKKYALLD STVLIFGETG TGKELFAQSI
HNASRRKNGP FVAINCAALP ENLLESELFG YAEGAFTGAR KGGKAGLFEL AHGGTIFLDE
IGEMPPGLQS KLLRVIQERR VMRIGDDRLI PVDVRIICAT NRELVEMIKQ GKFREDLFYR
INVLQINIPP LRERKEDLDV LVPHFIKKYS LGCGKYINGL TSRAMDFLKT FNFPGNVREL
ESIIERACAL CEGTLIDVGD IRFYQREESD VMPKMESHDI KPLEEIEREY IAKAIRLAGG
NLSEAARKLG VNRTTLWRKL KENKK
//
