ID   E8V0X2_TERSS            Unreviewed;       691 AA.
AC   E8V0X2;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE            EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN   OrderedLocusNames=AciPR4_1440 {ECO:0000313|EMBL:ADV82263.1};
OS   Terriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4).
OC   Bacteria; Acidobacteriota; Terriglobia; Terriglobales; Acidobacteriaceae;
OC   Terriglobus.
OX   NCBI_TaxID=401053 {ECO:0000313|EMBL:ADV82263.1, ECO:0000313|Proteomes:UP000006844};
RN   [1] {ECO:0000313|EMBL:ADV82263.1, ECO:0000313|Proteomes:UP000006844}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC BAA-1853 / DSM 23119 / SP1PR4
RC   {ECO:0000313|Proteomes:UP000006844};
RX   PubMed=23450133; DOI=10.4056/sigs.3036810;
RA   Rawat S.R., Mannisto M.K., Starovoytov V., Goodwin L., Nolan M., Hauser L.,
RA   Land M., Davenport K.W., Woyke T., Haggblom M.M.;
RT   "Complete genome sequence of Terriglobus saanensis type strain SP1PR4(T),
RT   an Acidobacteria from tundra soil.";
RL   Stand. Genomic Sci. 7:59-69(2012).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC       {ECO:0000256|ARBA:ARBA00006285}.
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DR   EMBL; CP002467; ADV82263.1; -; Genomic_DNA.
DR   RefSeq; WP_013567996.1; NC_014963.1.
DR   AlphaFoldDB; E8V0X2; -.
DR   STRING; 401053.AciPR4_1440; -.
DR   KEGG; tsa:AciPR4_1440; -.
DR   eggNOG; COG3525; Bacteria.
DR   HOGENOM; CLU_007082_5_1_0; -.
DR   Proteomes; UP000006844; Chromosome.
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR   InterPro; IPR015883; Glyco_hydro_20_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR029019; HEX_eukaryotic_N.
DR   PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR   PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR   Pfam; PF00728; Glyco_hydro_20; 1.
DR   Pfam; PF14845; Glycohydro_20b2; 1.
DR   PRINTS; PR00738; GLHYDRLASE20.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:ADV82263.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ADV82263.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006844};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           31..691
FT                   /note="beta-N-acetylhexosaminidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003228885"
FT   DOMAIN          39..151
FT                   /note="Beta-hexosaminidase eukaryotic type N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14845"
FT   DOMAIN          172..482
FT                   /note="Glycoside hydrolase family 20 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00728"
FT   ACT_SITE        328
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ   SEQUENCE   691 AA;  77594 MW;  86F8B96619A1D698 CRC64;
     MHKGHIIFKR LLAVLLGAGL FITAEVHAHA EDVRFVNTLM PQPSQLRLST GPAKISPEMK
     TTLHGSSNPL LQQATRRALD RLESMTQVLI DKNLQPTDTA TLDIAVEDVT ATHPVLQMDE
     SYSLDVQSGK VSLHAKTVFG AMHGLETLLQ LVQTQGTDFF FPAVHIADTP RFPWRGLMLD
     PGRRFLSVEE ILRTLDGMAA VKLNVLHWHL TEDQGFRIES KRFPKLHELG SEGQYYTQEQ
     VRQIIQYASA RGIRIVPEFD MPGHSTSWFV GYPELAAQPG PYHVEHVNHI FNAVMDPTRD
     STYKFLDTFF GEMAVLFPDE YMHIGGDESN GKDWSANPAI VRFMQQHNLK DSKALQAYFN
     LRVQVLLKKH GKQMVGWDEI LQPELAQDVV IQNWHGSEFL INGARQGHRG IFSKPYYLDH
     MYSAAEMYAA DPLPEGSPLS AAEAKLVLGG EACMWGEQIA TLTADSRIWP RAAAVAERLW
     SPMTIRDTED MYRRLEVTSL RLDALGITHL STPQRGLRQL AGSDAGAAKL AFFTSLLQPV
     DFHERGKEQH TSPLTPIGRL VDFTTSDPPS RRLLDAQIHA YLQATDPRMR EMHREELMDT
     FFRWLEVSSD LNTLAANHPL IAEVRVRREE LPALASLGIQ SIGYLESHTM PSAEWTAAQT
     GLLSRAAEHK ELVDYVVLDS LSVLLNATSR P
//