ID E8WT37_GEOS8 Unreviewed; 240 AA.
AC E8WT37;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Pyruvate dehydrogenase complex repressor {ECO:0000256|ARBA:ARBA00039592};
GN OrderedLocusNames=GM18_2791 {ECO:0000313|EMBL:ADW14237.1};
OS Geobacter sp. (strain M18).
OC Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC Geobacteraceae; Geobacter.
OX NCBI_TaxID=443143 {ECO:0000313|EMBL:ADW14237.1, ECO:0000313|Proteomes:UP000001442};
RN [1] {ECO:0000313|EMBL:ADW14237.1, ECO:0000313|Proteomes:UP000001442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M18 {ECO:0000313|EMBL:ADW14237.1,
RC ECO:0000313|Proteomes:UP000001442};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Chertkov O., Munk C., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Ovchinnikova G., Pagani I., Holmes D.,
RA Aklujkar M., Lovley D., Woyke T.;
RT "Complete sequence of Geobacter sp. M18.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcriptional repressor for the pyruvate dehydrogenase
CC complex genes aceEF and lpd. {ECO:0000256|ARBA:ARBA00037357}.
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DR EMBL; CP002479; ADW14237.1; -; Genomic_DNA.
DR AlphaFoldDB; E8WT37; -.
DR STRING; 443143.GM18_2791; -.
DR KEGG; geb:GM18_2791; -.
DR eggNOG; COG2186; Bacteria.
DR HOGENOM; CLU_017584_9_5_7; -.
DR OrthoDB; 5343675at2; -.
DR Proteomes; UP000001442; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 1.20.120.530; GntR ligand-binding domain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011711; GntR_C.
DR InterPro; IPR008920; TF_FadR/GntR_C.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43537:SF34; PYRUVATE DEHYDROGENASE COMPLEX REPRESSOR; 1.
DR PANTHER; PTHR43537; TRANSCRIPTIONAL REGULATOR, GNTR FAMILY; 1.
DR Pfam; PF07729; FCD; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00895; FCD; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF48008; GntR ligand-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 9..77
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 240 AA; 27377 MW; BF94DFC0DF69821A CRC64;
MKFTPIKPKK VSTQIAEQIR SSILAGEFNP GEKLPPEREL ADMFGVSRPS VREALNILTS
SGLVETYQGG GTLVRSLVEN AAGMPLTELI RIDGDRALDV IEVRMGMESW TAWYAATRAL
PEDIRRLEAV VDGMAKNLEE LKHSEDLDAH FHMLVARATH NVVWSHMMQS IFEAMQEFQR
DVWRAVYLTE EDQRLLYNHH LKVYEMIRDR NADGARDAML EHLDFAQKRC SAYVTMRGSE
//
