ID E8X8R7_SALT4 Unreviewed; 305 AA.
AC E8X8R7;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=DNA-binding transcriptional activator GcvA {ECO:0000313|EMBL:ADX18770.1};
GN Name=gcvA {ECO:0000313|EMBL:ADX18770.1};
GN OrderedLocusNames=STM474_3128 {ECO:0000313|EMBL:ADX18770.1};
OS Salmonella typhimurium (strain 4/74).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=909946 {ECO:0000313|EMBL:ADX18770.1, ECO:0000313|Proteomes:UP000008978};
RN [1] {ECO:0000313|EMBL:ADX18770.1, ECO:0000313|Proteomes:UP000008978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4/74 {ECO:0000313|Proteomes:UP000008978};
RX PubMed=21478351; DOI=10.1128/JB.00394-11;
RA Richardson E.J., Limaye B., Inamdar H., Datta A., Manjari K.S.,
RA Pullinger G.D., Thomson N.R., Joshi R.R., Watson M., Stevens M.P.;
RT "Genome sequences of Salmonella enterica serovar typhimurium, Choleraesuis,
RT Dublin, and Gallinarum strains of well- defined virulence in food-producing
RT animals.";
RL J. Bacteriol. 193:3162-3163(2011).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; CP002487; ADX18770.1; -; Genomic_DNA.
DR RefSeq; WP_000044409.1; NC_016857.1.
DR AlphaFoldDB; E8X8R7; -.
DR GeneID; 66757291; -.
DR KEGG; seb:STM474_3128; -.
DR PATRIC; fig|909946.3.peg.3200; -.
DR HOGENOM; CLU_039613_37_1_6; -.
DR Proteomes; UP000008978; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08432; PBP2_GcdR_TrpI_HvrB_AmpR_like; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30537:SF26; GLYCINE CLEAVAGE SYSTEM TRANSCRIPTIONAL ACTIVATOR; 1.
DR PANTHER; PTHR30537; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000313|EMBL:ADX18770.1}.
FT DOMAIN 6..63
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 305 AA; 34391 MW; FF8534E78F81DA9C CRC64;
MSKRLPPLNA LRVFDAAARH LSFTRAAEEL FVTQAAVSHQ IKSLEDFLGL KLFRRRNRSL
LLTEEGQSYF LDIKEIFSQL TEATRKLQAR SAKGALTVSL PPSFAIQWLV PRLSSFNSAY
PGIDVRIQAV DRQEDKLADD VDVAIFYGRG NWPGLRVEKL YAEYLLPVCS PLLLTGEKPL
KTPEDLAKHT LLHDASRRDW QAYTRQLGLN HINVQQGPIF SHSAMVLQAA IHGQGIALAN
NVMAQSEIEA GRLVCPFNDV LVSKNAFYLV CHDSQAELGK IAAFRQWILA KAATEQEKFR
FRYEQ
//
