ID E9AGI6_LEIIN Unreviewed; 866 AA.
AC E9AGI6; A0A2K4YP41; A0A381MCL6;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CBZ08486.1};
GN ORFNames=LINJ.12.0820 {ECO:0000313|EMBL:CBZ08486.1};
OS Leishmania infantum.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=5671 {ECO:0000313|EMBL:CBZ08486.1, ECO:0000313|Proteomes:UP000008153};
RN [1] {ECO:0000313|EMBL:CBZ08486.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CBZ08486.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=17572675; DOI=10.1038/ng2053;
RA Peacock C.S., Seeger K., Harris D., Murphy L., Ruiz J.C., Quail M.A.,
RA Peters N., Adlem E., Tivey A., Aslett M., Kerhornou A., Ivens A.,
RA Fraser A., Rajandream M.A., Carver T., Norbertczak H., Chillingworth T.,
RA Hance Z., Jagels K., Moule S., Ormond D., Rutter S., Squares R.,
RA Whitehead S., Rabbinowitsch E., Arrowsmith C., White B., Thurston S.,
RA Bringaud F., Baldauf S.L., Faulconbridge A., Jeffares D., Depledge D.P.,
RA Oyola S.O., Hilley J.D., Brito L.O., Tosi L.R., Barrell B., Cruz A.K.,
RA Mottram J.C., Smith D.F., Berriman M.;
RT "Comparative genomic analysis of three Leishmania species that cause
RT diverse human disease.";
RL Nat. Genet. 39:839-847(2007).
RN [2] {ECO:0000313|EMBL:CBZ08486.1, ECO:0000313|Proteomes:UP000008153}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JPCM5 {ECO:0000313|EMBL:CBZ08486.1,
RC ECO:0000313|Proteomes:UP000008153};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
RN [3]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JPCM5;
RA Hilley J.D., Rogers M., Wilkes J., Dickens N.J., Bates P., Depledge D.P.,
RA Harris D., Her Y., Herzyk P., Imamura H., Otto T.D., Saad W., Seeger K.,
RA Berriman M., Smith D.F., Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow genomic structural
RT differences between species and strains of Leishmania.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FR796444; CBZ08486.1; -; Genomic_DNA.
DR RefSeq; XP_003392338.1; XM_003392290.1.
DR AlphaFoldDB; E9AGI6; -.
DR SMR; E9AGI6; -.
DR STRING; 5671.E9AGI6; -.
DR GeneID; 10966308; -.
DR KEGG; lif:LINJ.12.0820; -.
DR VEuPathDB; TriTrypDB:LINF_120016600; -.
DR eggNOG; ENOG502SB5P; Eukaryota.
DR InParanoid; E9AGI6; -.
DR OMA; ESACCCS; -.
DR OrthoDB; 129128at2759; -.
DR Proteomes; UP000008153; Chromosome 12.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008153}.
FT COILED 154..181
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 468..495
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 672..699
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 866 AA; 95509 MW; 8A76D117505B7464 CRC64;
MMNARRASSM DRSAVAGFDP VSHYSSCPPL PVIRQPQSTA LSACDACTAP HAGLRQHESG
VAALKPSRKA ASPPYVITDK TPRPELLAII MQLQADLTQR TDSVNAIQRN FERLSAMHHA
EQLELRRLRL LEKTRPESAP DGGDAATRQL ESVLAEMRHR AVEQQATFAQ MEEELQAANR
LCALHQGIAR LIASHADGFR DVLQAEALAH SQLYKSAMSE RAGIGSRHEA TQQQLLCKDV
AQLVADHQAQ IVPKLIRGGA AERCRMKNPA QVSTATLLEL VRQGLRETAE AVHQYVAATH
ATDQERVLTE AEGQRDREEL RRVLGELLRL RRRATEEAEA TARTALLFGA LQTSVTAHRA
FDQVRLLTAN ADAAAAATRS SWEVTAALLT RRISDWRDAA DVRLVDFCNT IEASMAEKAR
ERDAQTQQTA QELLLDERKR LENLHASQVQ TMQADWRRQR DAVQQSHAKQ LEQVRRDLVA
QVQVAEDRRA AAERRTGAIE AALTQMTRDH AAEVQAVEAH WRSAVLDAER HCEQRWRTML
EAYQEGQKAS RGAVLQLMVD VLRTRGHCVY EEQAERAALC RSHWRNQTQH LREEQAAVMQ
HGVATAVVLE RMRYHTEDEA ASRAVLHASE AADWAALVRK EAAHNAQVHH AVSMAAAAAR
LEGLRAEMAG REARWEQRLD ALETDLRQAQ QECLGAVHRA SDAVVAAQEA QAALQATQRD
FAAYRCGVGA AAQRIEVAES ATESACCCSL CLELYCQPVA CVPCGHIYCA NCLLRHARNR
SLPSVASAFA CGAGASTGEN GAVGARAQLE VTHWLRNMST PHASLFCPEC ASTTVSTVVE
LPILGELTAK YDYKKRSLAV LLAELR
//
