ID E9ARF5_LEIMU Unreviewed; 347 AA.
AC E9ARF5;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=RRM domain-containing protein {ECO:0000259|PROSITE:PS50102};
GN ORFNames=LMXM_18_0180 {ECO:0000313|EMBL:CBZ25526.1};
OS Leishmania mexicana (strain MHOM/GT/2001/U1103).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Leishmaniinae; Leishmania.
OX NCBI_TaxID=929439 {ECO:0000313|EMBL:CBZ25526.1, ECO:0000313|Proteomes:UP000007259};
RN [1] {ECO:0000313|EMBL:CBZ25526.1, ECO:0000313|Proteomes:UP000007259}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/GT/2001/U1103 {ECO:0000313|EMBL:CBZ25526.1,
RC ECO:0000313|Proteomes:UP000007259};
RX PubMed=22038252; DOI=10.1101/gr.122945.111;
RA Rogers M.B., Hilley J.D., Dickens N.J., Wilkes J., Bates P.A.,
RA Depledge D.P., Harris D., Her Y., Herzyk P., Imamura H., Otto T.D.,
RA Sanders M., Seeger K., Dujardin J.C., Berriman M., Smith D.F.,
RA Hertz-Fowler C., Mottram J.C.;
RT "Chromosome and gene copy number variation allow major structural change
RT between species and strains of Leishmania.";
RL Genome Res. 21:2129-2142(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FR799571; CBZ25526.1; -; Genomic_DNA.
DR RefSeq; XP_003874032.1; XM_003873983.1.
DR AlphaFoldDB; E9ARF5; -.
DR GeneID; 13447708; -.
DR KEGG; lmi:LMXM_18_0180; -.
DR VEuPathDB; TriTrypDB:LmxM.18.0180; -.
DR OMA; DCAGADT; -.
DR OrthoDB; 120209at2759; -.
DR PhylomeDB; E9ARF5; -.
DR Proteomes; UP000007259; Chromosome 18.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00590; RRM_SF; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR PANTHER; PTHR24012; RNA BINDING PROTEIN; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SMART; SM00361; RRM_1; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 18..96
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 111..197
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 347 AA; 38372 MW; 8894F8C5FE8CCFBC CRC64;
MSKNSPHKHK SSFTPSSTNL FVRYLPREVD DNRLREIFSA FGNITSSMVM RDIYSGQSLG
TAFVRYEEHE EALRAMRDAH GMPLLGKTVS VQWAKQQHDD TPAGQERLRM NKLFLRNVPL
EVTEEDLVHL VSPYGSVRKV TMHNDTAPLI DATERRRIVF ITFSEQGAAE AALLAVHNTC
AFHQCRGIPL MGKLSEDYTQ KMRTPRTAHV PHSWQYGGSE RSPSSSYLKA VKLCSEDPAP
PVLGRCASGM NAADCTGIDT PRGMETPRRV GTALMSCPSH SQCTATMAVM RGLGNTQRVA
AERTGFVAAP RCTCETFVGP TTIHALDSGI TVTIRHRPSS RTFKGYS
//
