ID E9CS24_COCPS Unreviewed; 1219 AA.
AC E9CS24;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Intermediate filament protein Mdm1 {ECO:0000313|EMBL:EFW23345.1};
GN ORFNames=CPSG_01244 {ECO:0000313|EMBL:EFW23345.1};
OS Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=443226 {ECO:0000313|Proteomes:UP000002497};
RN [1] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
RN [2] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Orbach M., Henn M.R., Cole G.T., Galgiani J., Gardner M.J.,
RA Kirkland T.N., Taylor J.W., Young S.K., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R., Freedman E.,
RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA Howarth C., Jen D., Larson L., Mehta T., Neiman D., Park D., Pearson M.,
RA Richards J., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Coccidioides posadasii strain Silveira.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; GL636486; EFW23345.1; -; Genomic_DNA.
DR STRING; 443226.E9CS24; -.
DR VEuPathDB; FungiDB:CPSG_01244; -.
DR VEuPathDB; FungiDB:D8B26_006837; -.
DR eggNOG; KOG2101; Eukaryota.
DR HOGENOM; CLU_002131_1_0_1; -.
DR OMA; AMYVVEV; -.
DR Proteomes; UP000002497; Unassembled WGS sequence.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06876; PX_MDM1p; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002497}.
SQ SEQUENCE 1219 AA; 136965 MW; C8F3D7422DFBBA35 CRC64;
MALGRRDILI ASFGGLLAWG LLVEWLPVLR FLGYSFAFGA ALTALTIGAL VVLTVRDGFD
HRARPVSLAG TSIAFLSPQN WEEHCGSYRV DVKYQPEPLY PQSFIVSAAL DELLQFAIRD
FIRSWYGNIS SNLKFANEID RAIRTAIHNL RARLESEDLV EILVSRIVPI LTAHFKEFDK
AERAVRGKNL THNVTESEEL DIAIASRYRD GNLHPATSPS FPDKNNAQQN HLRKIVVSLL
PGLVPSTLLD SRAVSILIRE IIACAILFPL MDLLADPDSW NQLVEAYGQA TIQDRKTVRK
LRAALDQHAS AIPRSKRSQQ FPKLAPNDSE RDFERFVRAI RRCNNLSDAR KFRSHIASQL
KRENMIDGQD QVYLRRLETG KRVLDQKVAK LSALGGHSSP QVNADLRYSY ISKPHEVSLV
DIMHNASGLS YFMEYMDRHR LMSLVQFWIV VDGFRNPLED DFGDDTPTRS VTWTATDRND
MILISENHLS KPELRVPEES RKAVKEFISA GKRATPEQYR RARTAILTTQ SMVLEEMQNK
YYPGFQKSDL YYKYLASDEA ATVSSAPLER KVLNRSPASD MFPAALQRTG SQSSCQSRDM
RKPFPANEAP KLSLLTDALP TERRSLLDSP RAPLFSDEIE PDPMESSTYS PGQGSHNGDG
EMQDSRIIAN MEAALNDIMS NEPHEIKPEE SKSGFGSPFS LPYPVRDGDS ARSSFDSTRP
HGNLPEKPKP SIASLGLVNT SSRIGVFTDD DLFPDQKKFI EDEYADEVMD ETQSPEDEIH
EAAPGDLGLT EAISALSADI EKLMSQEAIV GALTRKAELT NNTAELRILG KSRSSLQREI
RRKEMQRQQY ILQESDNSLY GRSTVQIKSI IVGKEEDGRE YALYLIEVTR KAGEQMPAAS
WAVPRRYSEF HELHHQLRTR YPAVRPLEFP RRRVVMKLQK DFLHKRRLGL EAYLQQLLLL
PDVCRSRELR AFLSQRAILP ATHSSGTPRE GEGRDLVTRI YNSVTDSVDD ILGSIPVFDQ
LSAAGQNLIS AATTQRSFTP QPGLITPEDS LTAAEAEAEL SAFEDRELEP FVKPICDIFL
EIFELNKGNN WLRGRAVVVV LHQLLGGTIE RKIRDNAKSL VQDTALLRYI SLIKDTMWPG
GKLRENKPRT LAEKMKSRTD ASVVLATLIP DLAGSVVGRA NAQAAARRIF ATTNNRRLNL
HLAYEILDEI VEVLLGSGR
//
