ID E9CXI3_COCPS Unreviewed; 645 AA.
AC E9CXI3;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 03-MAY-2023, entry version 32.
DE SubName: Full=Alkaline phosphatase {ECO:0000313|EMBL:EFW20660.1};
GN ORFNames=CPSG_02503 {ECO:0000313|EMBL:EFW20660.1};
OS Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=443226 {ECO:0000313|Proteomes:UP000002497};
RN [1] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
RN [2] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Orbach M., Henn M.R., Cole G.T., Galgiani J., Gardner M.J.,
RA Kirkland T.N., Taylor J.W., Young S.K., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R., Freedman E.,
RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA Howarth C., Jen D., Larson L., Mehta T., Neiman D., Park D., Pearson M.,
RA Richards J., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Coccidioides posadasii strain Silveira.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL636488; EFW20660.1; -; Genomic_DNA.
DR AlphaFoldDB; E9CXI3; -.
DR STRING; 443226.E9CXI3; -.
DR VEuPathDB; FungiDB:CPSG_02503; -.
DR VEuPathDB; FungiDB:D8B26_003005; -.
DR eggNOG; ENOG502QU5W; Eukaryota.
DR HOGENOM; CLU_015982_0_0_1; -.
DR OMA; SCANWEA; -.
DR Proteomes; UP000002497; Unassembled WGS sequence.
DR CDD; cd07389; MPP_PhoD; 1.
DR Gene3D; 3.60.21.70; PhoD-like phosphatase; 1.
DR Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR018946; PhoD-like_MPP.
DR InterPro; IPR038607; PhoD-like_sf.
DR InterPro; IPR032093; PhoD_N.
DR PANTHER; PTHR43606; PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08710)-RELATED; 1.
DR PANTHER; PTHR43606:SF2; PHOSPHATASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G08710)-RELATED; 1.
DR Pfam; PF09423; PhoD; 1.
DR Pfam; PF16655; PhoD_N; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002497};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..645
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003234456"
FT DOMAIN 61..199
FT /note="Phospholipase D N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16655"
FT DOMAIN 212..576
FT /note="PhoD-like phosphatase metallophosphatase"
FT /evidence="ECO:0000259|Pfam:PF09423"
SQ SEQUENCE 645 AA; 72213 MW; 51942A97F586E35B CRC64;
MRYSLGLLAL SAATASASFA GNLNYRSPSA NHPSLGVSVP KVEKRSEPGS AFDPAQLNFT
HGVASGDPYA TSVILWTRCS PMFDDVNDNS TVSGLVPMYN PVPIYKDTDE HRPISNAPVC
LRFKVATDDK LKRVVDEGTV YTSSDVDYTV KASTVIPMNQ HRRPLILVEA TKLKPFTTYY
YQFSVCGSNK KSPIGRTKTA PKASRSVDRI NLAVFSCSNY PFGFFNAYGN VARKDSVDYV
LHLGDYIYEY ADGEYGSGKD IGRLSLPDRT IYTLYDYRKR LATYRTDLDL QANHQNFAWI
PVWDDHEVAD NSYRDGSSEL NNTEASFITS GGISVDQRKM NAVRAYFEWM PIRQVDMDDN
LRIWRNFQLG SLVDVIMLDT RNYDRSITNL YWNKDYVDQL KNEPNRSLMG SKQENWLYRN
LIQSAKRGAK WRIIGSQIVF SYIDESAAFG DNRAFNLDAW NGYQANRNRT FKTLFDNKID
NNILIAGDSH ANWVSDLVWL GQKEYDPATG AGAIGVEFGG SAVTSSSPAG RNIDIKDSIN
ASKALVTTNP VLQWSELYYR GYFELHITPK EVDARFFGTP KLRVRNPGEI SLANFTVKSG
ANRLDRGPVG VPAGGIVENG WLKGGKVVQT NVTNSTDTGR WYISN
//
