ID E9D2U9_COCPS Unreviewed; 1389 AA.
AC E9D2U9;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Peptidase S8/S53 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CPSG_03897 {ECO:0000313|EMBL:EFW19513.1};
OS Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=443226 {ECO:0000313|Proteomes:UP000002497};
RN [1] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
RN [2] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Orbach M., Henn M.R., Cole G.T., Galgiani J., Gardner M.J.,
RA Kirkland T.N., Taylor J.W., Young S.K., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R., Freedman E.,
RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA Howarth C., Jen D., Larson L., Mehta T., Neiman D., Park D., Pearson M.,
RA Richards J., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Coccidioides posadasii strain Silveira.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL636490; EFW19513.1; -; Genomic_DNA.
DR STRING; 443226.E9D2U9; -.
DR VEuPathDB; FungiDB:CPSG_03897; -.
DR VEuPathDB; FungiDB:D8B26_007735; -.
DR eggNOG; ENOG502SKQZ; Eukaryota.
DR HOGENOM; CLU_255440_0_0_1; -.
DR OMA; YIINNGW; -.
DR Proteomes; UP000002497; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002497};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT REGION 192..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 313..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1105..1188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1231..1253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..277
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..342
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..357
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1106..1188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1389 AA; 150700 MW; BDAABDDB6CFEB001 CRC64;
MPAENQNFTR QRALTTAPDR RWPHTVANLS SYGGYNATLS SGGLSVGAGN MTLPAITQLS
RSRTVGMTST VGYTTPPGLG GPVVIIVSTK TATLPAVTSS TKLLTLGHTF ILTPPAILSS
AQAYPTLIIV GNETVTFSNV STITMPASSK TTFPLTPQMS TNASFGSNPA TSVTVVDGTR
SLTFPSPSKQ TAVTLEGQTT TTQVPSRPPN NTAVLSPLPA TKNNTMTPVM VAIGNSTFTF
SPGIQKTIVT IRGHTVTLDP EQSPTISSSS RAPSATAMTR RRGTAPAISL EPTLSNSRST
TLVRANPTVT NVNVSFEPSS ATGRATGTDR SSSSSRETTV TSHTAKPEIE EETTARTKSP
SRLPLPTGTM AETEDSPMPT LVRWPPEAMI TPVETEVKKP QLSEDDNDSA VIPCKLWFFS
ACLRFDNINI LGWKITFPPG IYPPGPPPIQ NLKFPPPIGF QGDLPPWPKF TVGSDRIPTF
PPEPEPTKCE TRTASLCSTS TSFVVSTVRG ALQTISSQVL PPTCAEVRGC IVEDFTKIAS
LTTTQGCRTG TATDVVITCS GSETSACATQ TKIPRTGCSV TATTTTVSCT PAPPGKGRRH
TGGEVCAPEE LYIVWPRDGT DVAETSAIYS EMKKLLKDEG KIRASDTKTM GINFWRVFSE
PGQIQKIREI PNVVGVHREC TSDCADPLDN VQSKWRYQDN YLEIELEGSI LGRQQMVYLS
QNKLPEQRFH NHYFFDVEAG RDIPVFIVDT GAQLDHQEFT EGDNIASKTE FVFVEKDYDG
QYHRDDAGVP LNGVCEPGYC NPHGTGMLGM IAGANLGVAK KVKPWVVRVP RKNKRGGGFT
PQHFLEGVAR VNDMILGDSK TTRAILSLSW SYDSEKFIKG SDASTDDFET WRVRFHGILR
TLIQKGVFVV TGSGNNYIVN GWPALFGAEP STLKPELQAN WLHVPELLVV GAVDVFTGER
WWKSAIDVDK GLPHIYAPGK HVLGTQGNKG EWRRDFEGTY KVEVGTSVAT AYAAGLAAYF
LRLHQVGRLG PDAKGNDPDM SPAGLKRYII NNGWSRYHEK YVGDIVGIWN GAAIPRLKEQ
GYCRYRPKDA RDPFKLRRRG SDSQLTDLCL PGTSKTQSIG QSINTSTSSP TNKSTAKPTD
TRKNKSIGTA IAKSTAKSTS KSTIKPTGEQ AGKSTRSTSS RHTTSAKPTN FVCTEETADQ
CSPGIICNAP RLNGCIDGEC VCILPDPPPT TSRTTTLTSK AKSPKPTVEK KPKEPLALGE
RHCHNKSLFD GDSEIKERYV ARFSFLLCKH CYDDDVAFHP GKKPITFNTR ANGAPYFVSI
SWKDGCEMTI DRVKVFRPLQ ETSIVAANRN VNCFELLYNN WRKCTGNKGR GGYIDVGCVR
YELAAKDKS
//
