ID E9D5L5_COCPS Unreviewed; 686 AA.
AC E9D5L5;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=NAD+ kinase {ECO:0000313|EMBL:EFW18209.1};
GN ORFNames=CPSG_04895 {ECO:0000313|EMBL:EFW18209.1};
OS Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=443226 {ECO:0000313|Proteomes:UP000002497};
RN [1] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
RN [2] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Orbach M., Henn M.R., Cole G.T., Galgiani J., Gardner M.J.,
RA Kirkland T.N., Taylor J.W., Young S.K., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R., Freedman E.,
RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA Howarth C., Jen D., Larson L., Mehta T., Neiman D., Park D., Pearson M.,
RA Richards J., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Coccidioides posadasii strain Silveira.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NAD kinase family.
CC {ECO:0000256|ARBA:ARBA00010995}.
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DR EMBL; GL636492; EFW18209.1; -; Genomic_DNA.
DR STRING; 443226.E9D5L5; -.
DR VEuPathDB; FungiDB:CPSG_04895; -.
DR VEuPathDB; FungiDB:D8B26_005046; -.
DR eggNOG; KOG2178; Eukaryota.
DR HOGENOM; CLU_008831_7_2_1; -.
DR OMA; EHMLKYW; -.
DR Proteomes; UP000002497; Unassembled WGS sequence.
DR GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR GO; GO:0019674; P:NAD metabolic process; IEA:InterPro.
DR GO; GO:0006741; P:NADP biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR HAMAP; MF_00361; NAD_kinase; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR017437; ATP-NAD_kinase_PpnK-typ_C.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR InterPro; IPR002504; NADK.
DR PANTHER; PTHR20275; NAD KINASE; 1.
DR PANTHER; PTHR20275:SF0; NAD KINASE; 1.
DR Pfam; PF01513; NAD_kinase; 1.
DR Pfam; PF20143; NAD_kinase_C; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EFW18209.1};
KW NAD {ECO:0000256|ARBA:ARBA00023027}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW Reference proteome {ECO:0000313|Proteomes:UP000002497};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 686 AA; 74890 MW; 8FA2C5DE22B5420F CRC64;
MSPFVPPSPL SISHTPSHPD PHPQRRQLPS SSAAQEHGDA ASCGEASAVS RQSPEAGSRA
IHRGSALNLT PIIPTDPQMT DHGRSSTDEA PADLLPSLEP SVSRESRTIA SLPASPFQHI
PHRPAPISSR NHHHHQSAKS IDGIPRQTLM KALASQASSS AESPSLSIAT SLAEMLSPTS
NAGSDQQTGD TRLHRQLSAA LSAKPLTFSD GDTPSTARFP LKSPCYYHQR FDGAVNIQRV
LEEIAADEWM SHSRLMQTAT GVREVSKQLQ RRPIKVAVKN VMIVTKARDN GLVYLTRELA
EWLLSTPRYG SDLGVNVYVD SKLRRSARFD APGLLRKEPR FESMLKYWTP DLCWTSPETF
DLVITLGGDG TVLFTSWLFQ RIVPPILAFS LGSLGFLTNF EFSKYKEHLN HIMGDVGMRV
NLRMRFTCTV YRADHSNKHR PGAVEEGEQF EVVNELVIDR GPSPYVSNLE VYGDDELLTI
VQADGCILST PTGSTAYSLS AGGSLIHPSI PAILLTPICP HTLSFRPMVL SDTLLLRIAI
PPGSRSTAYC SFDGKGRIEL CPGDYVTLEA SQYPFPTVVS GGGEWFESVR RTLCWNVRGA
VQKGWSSKSH RPEGEQMGLD PMGTPRGQAP EAVADEQDDE EEKWDIDTDS YTDFGQGTDS
GLGPSECGDS PGTTSPLKRV MSLLNM
//
