ID E9DGN4_COCPS Unreviewed; 1297 AA.
AC E9DGN4;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Ankyrin repeat domain-containing protein 28 {ECO:0000313|EMBL:EFW14395.1};
GN ORFNames=CPSG_08983 {ECO:0000313|EMBL:EFW14395.1};
OS Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=443226 {ECO:0000313|Proteomes:UP000002497};
RN [1] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
RN [2] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Orbach M., Henn M.R., Cole G.T., Galgiani J., Gardner M.J.,
RA Kirkland T.N., Taylor J.W., Young S.K., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R., Freedman E.,
RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA Howarth C., Jen D., Larson L., Mehta T., Neiman D., Park D., Pearson M.,
RA Richards J., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Coccidioides posadasii strain Silveira.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL636506; EFW14395.1; -; Genomic_DNA.
DR STRING; 443226.E9DGN4; -.
DR VEuPathDB; FungiDB:CPSG_08983; -.
DR VEuPathDB; FungiDB:D8B26_008252; -.
DR VEuPathDB; FungiDB:D8B26_008253; -.
DR eggNOG; KOG4177; Eukaryota.
DR HOGENOM; CLU_001887_0_0_1; -.
DR OMA; GMFLCAW; -.
DR Proteomes; UP000002497; Unassembled WGS sequence.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24193:SF121; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24193; ANKYRIN REPEAT PROTEIN; 1.
DR Pfam; PF12796; Ank_2; 3.
DR SMART; SM00248; ANK; 11.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 6.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000002497};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..1297
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003238277"
FT REPEAT 922..954
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 955..987
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 988..1020
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1089..1122
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1123..1155
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1156..1188
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 149..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..171
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1297 AA; 144842 MW; 3FE13761631349F7 CRC64;
MKFSILVLFV FASLVFAQDE WDDFYNNFAT DLTPLLALFG EQVTKQFLSE STSLLDNVIF
AAAPLGILTA IVSVIRVCGS PSLRAFIGRA QEGRGIAEVE LCSSTSNDIL ELIYDKNNGA
FYDSSGSPSK AHLFPSREYF QQKKLEAVGG REVDDGDTQN FTDEDPLEKE ESPTSAGTVL
LVTGMFLCAW LIETTTEEKV FKKRVRMYWL QQGGQTIGDQ VFDAFAHSAD LDEYMTSWKR
EGPITRAREG LVWLAVGSTS VGFVLQFVGL RGLHSFVALF QLGATVIMAI VRAGLRPQRL
GEGRNELRDS GSSVNGHELD WFAHRVDREN CPQRFLEGTW EVYPTVPRCP NEDPGENKIQ
VSGLYGDVSE SGSETMKSVI KWISSLQSDG TEASENPHIA ARILYYRARL SRLTQEQSTS
LPEEWQIDVR RHAQSLKIAL EDVARIIFSG RFQLKQGWED ISAIFWTVDI VTESPDEGVR
PIHVIIKRVN GAWRTDLSEL GAILGLWIWS IRNGSKYTIP NPDKFFALVR SWDEVERVKL
DLLTWVSGSL KRDFAVWECY DPEFDIACRD LDHLPVLSVP LSIQKRNSLY GYSQSFNCNA
KALYVSTRHG LPLMCAQDIF TIFICRVVNA IQDISDFEPF LEAGGDTVRS QDGSFRLVNR
HIDSIAEAFR NAGLGSREDA LTSMIPILRA HSLLVIPENI KTSVLTLAAE RRRKNDFVNA
EDMLRWIYHN LNNGTPTEQK VLTRELGELY RRALQAEDIR TRSFGYNGIL NVLDTFQGSE
RVDEIKQNYI WAAVQFASIN QDLTYRAALS KAMKRNLADG LDNMSISAAL KCEPFYPVCL
IIATKWRAEV CDPIPHLDVP PLCLAARRGC WELVEDLLSL SFDINAQDQE GRTGMFFAAE
WGHYDTVRCL LDYNAALGPN NLNQSPLWIA AANGHNTVVE LLLENGANPE QQDIGGCSPL
WIAAANQHEA TVRMLLGRNA DVNSRNIDGD TPLMATARTR SEAVLSLLLD FGADMNAKAR
DGYNALSYAI SSKCIENISL FLDRGCHLED RNGLGWTALL TAVGSCEPSG EMVAFLLDEG
AYVEAKDERG RTPLLVAAEM NRPLEVIRAL LARKAAVNAT DAKNLTPLDF VVINRRADIT
QLLLEFGADT ECKGNNYMTP LFQAVANGDA AIAELLLEHG ADPSHHAAGV SVLTKSIDVE
RFDITAMLLK KGAFLGHWYE DVNAYFCRVM ETQDEELVRL LLKHCKNLQA HWQILQRAEE
IGNERIVKML LDHGVRPYPK SPAREAAKTG KPDYKAI
//
