ID E9DS93_METAQ Unreviewed; 704 AA.
AC E9DS93;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Mitochondrial carrier protein, putative {ECO:0000313|EMBL:EFY93253.1};
GN ORFNames=MAC_00491 {ECO:0000313|EMBL:EFY93253.1};
OS Metarhizium acridum (strain CQMa 102).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655827 {ECO:0000313|Proteomes:UP000002499};
RN [1] {ECO:0000313|EMBL:EFY93253.1, ECO:0000313|Proteomes:UP000002499}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CQMa 102 {ECO:0000313|EMBL:EFY93253.1,
RC ECO:0000313|Proteomes:UP000002499};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
CC -!- SUBUNIT: Homodimer (via N-terminus). {ECO:0000256|ARBA:ARBA00038674}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375}.
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DR EMBL; GL698471; EFY93253.1; -; Genomic_DNA.
DR RefSeq; XP_007806831.1; XM_007808640.1.
DR AlphaFoldDB; E9DS93; -.
DR STRING; 655827.E9DS93; -.
DR GeneID; 19244802; -.
DR KEGG; maw:MAC_00491; -.
DR eggNOG; KOG0751; Eukaryota.
DR HOGENOM; CLU_014931_2_0_1; -.
DR InParanoid; E9DS93; -.
DR OMA; GPDAIPF; -.
DR OrthoDB; 1220009at2759; -.
DR Proteomes; UP000002499; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0043490; P:malate-aspartate shuttle; IEA:UniProt.
DR CDD; cd00051; EFh; 2.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR45678:SF9; CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1; 1.
DR PANTHER; PTHR45678; MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Reference proteome {ECO:0000313|Proteomes:UP000002499};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 105..140
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 177..212
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REPEAT 345..435
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 443..531
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 541..629
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 704 AA; 78216 MW; E8540B5DB937F889 CRC64;
MASPSTLVKE VVKETLKGSG APEDPSHQLS AQSKARFNAH AAKDPETGEL YMGPEEFTNA
IAPVTEDYHK IKRDQYSILF RVADNKGRGR LSLADWGVFE NLLMKPDAEY EIAFRLFDVD
RTGDVKYDDF RRLYELNKGP DNIPFDWDCE WAKLYIGSKK KRHNLSYPQF SQMLRGLQGE
RIRQAFQLLD KDGDGYIEPE EFARIILETS KHKLSDHILA NLHTLCNITT GSKISYASVR
AFQNMIKEMD LVELIVRRAI SRSSDGKITR AEFVNEASRV TRFSLFTPME ADILFHFASL
DEPSGRLGLR DFAKVLDPSW RNPMYDVDEP SVPVTKKASI FHGILESTYN FALGSVAGAF
GAFMVYPIDL VKTRLQNQRG AQPGQRLYKN SIDCFQKVFR NEGIRGLYSG VLPQLVGVAP
EKAIKLTVND LVRGYFTDKQ GRIPVSAEIL AGASAGGCQV VFTNPLEIVK IRLQVQGEVA
KSVEGTPKRS AMWIVRNLGL VGLYKGASAC LLRDVPFSAI YFPTYSHLKR DFFGETPANK
LGVLQLLTAG AIAGMPAAYL TTPCDVIKTR LQVEARKGEA SYTGLRHAAK TIWKEEGFTA
FFKGGPARIF RSSPQFGFTL AAYEVLQTLL PMPGGKKEEK LAGVGDVMSA VTKSRTLDTS
PFARSRNALK IILDLDEDFG RSKIPDANRW KSLPKVMGGG GAAQ
//
