ID   E9DZG6_METAQ            Unreviewed;       682 AA.
AC   E9DZG6;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=mRNA export factor mex67 {ECO:0000313|EMBL:EFY90898.1};
GN   ORFNames=MAC_03014 {ECO:0000313|EMBL:EFY90898.1};
OS   Metarhizium acridum (strain CQMa 102).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX   NCBI_TaxID=655827 {ECO:0000313|Proteomes:UP000002499};
RN   [1] {ECO:0000313|EMBL:EFY90898.1, ECO:0000313|Proteomes:UP000002499}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CQMa 102 {ECO:0000313|EMBL:EFY90898.1,
RC   ECO:0000313|Proteomes:UP000002499};
RX   PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA   Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA   Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA   Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA   Wang C.;
RT   "Genome sequencing and comparative transcriptomics of the model
RT   entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL   PLoS Genet. 7:E1001264-E1001264(2011).
CC   -!- SIMILARITY: Belongs to the NXF family. {ECO:0000256|ARBA:ARBA00009285}.
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DR   EMBL; GL698486; EFY90898.1; -; Genomic_DNA.
DR   RefSeq; XP_007809354.1; XM_007811163.1.
DR   AlphaFoldDB; E9DZG6; -.
DR   STRING; 655827.E9DZG6; -.
DR   GeneID; 19247325; -.
DR   KEGG; maw:MAC_03014; -.
DR   eggNOG; KOG3763; Eukaryota.
DR   HOGENOM; CLU_024991_1_0_1; -.
DR   InParanoid; E9DZG6; -.
DR   OMA; YGGHEAW; -.
DR   OrthoDB; 10284at2759; -.
DR   Proteomes; UP000002499; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   CDD; cd14342; UBA_TAP-C; 1.
DR   Gene3D; 3.10.450.50; -; 1.
DR   Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR032710; NTF2-like_dom_sf.
DR   InterPro; IPR018222; Nuclear_transport_factor_2_euk.
DR   InterPro; IPR030217; NXF_fam.
DR   InterPro; IPR005637; TAP_C_dom.
DR   InterPro; IPR009060; UBA-like_sf.
DR   PANTHER; PTHR10662; NUCLEAR RNA EXPORT FACTOR; 1.
DR   PANTHER; PTHR10662:SF22; NUCLEAR RNA EXPORT FACTOR 1; 1.
DR   Pfam; PF03943; TAP_C; 1.
DR   SMART; SM00804; TAP_C; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF54427; NTF2-like; 1.
DR   SUPFAM; SSF46934; UBA-like; 1.
DR   PROSITE; PS51450; LRR; 1.
DR   PROSITE; PS50177; NTF2_DOMAIN; 1.
DR   PROSITE; PS51281; TAP_C; 1.
PE   3: Inferred from homology;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002499};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          409..583
FT                   /note="NTF2"
FT                   /evidence="ECO:0000259|PROSITE:PS50177"
FT   DOMAIN          611..664
FT                   /note="TAP-C"
FT                   /evidence="ECO:0000259|PROSITE:PS51281"
FT   REGION          1..111
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        34..50
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   682 AA;  74512 MW;  577A92FAF06FCD95 CRC64;
     MAPRGPRADA AQRANRGATN RTKATTKGGI QKRRVGVTRT DVDGDLDMDS VGKQAARGPG
     TETKVSKAKT AKAAPGKPTR GTSAAAKSSL KHLEGKNSKL SAASSGRATR ARGNGADLHF
     LRVHGLKQSK AASNPDGGLS DLLIFLERKA SSFTTGGQTP HIDIKETHMV GDYVFIGAAK
     EDADEILKLN TFTFAGAQLE IVESTEDLPG QSKVTRSKEG QELAAKFQSI LSQRYISANK
     LLKLDALASD AELVTMGMFQ NPDLAQRSFK GLMVICDELF KTEDEKKEAI ESISLANNSI
     NDVSEVDSVA TTFPYLKNLD MSGNQIANMA ALERWKGKFK SLVTLYMTGN PIDTTDPNYK
     TTLLQWFPNL QDINGVQVRT AEEIAEQEAA SRPKPIPQSG PDFRDVNGIG EKFLLEFFAA
     YDNDRQGLAS RLYDDQSQFS LAIDTQSVRD KDAPAPMGWG SYIKVSRNLM KITYQNARVQ
     RLFKGANVIY ELWKGLPPTK HPNIKDDLSK WIMDCHPLPA LADPTGQNPM GVDGLIIAVH
     GEFEEYDEKT NVVGKRSFSR SFVLGPGRPD KGPIRVVSDM LALRAFNALP NVFLAPNQAP
     GGSNNNTNTN SQHQAMIAEL CKQTGMVPQY SEMCLAQVGW DFDKALVIFN EKKAELPSEA
     FAVPPQFLMA RQKDSMDMLD GQ
//