ID E9EBY8_METAQ Unreviewed; 687 AA.
AC E9EBY8;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Ab-hydrolase associated lipase, putative {ECO:0000313|EMBL:EFY86608.1};
GN ORFNames=MAC_07386 {ECO:0000313|EMBL:EFY86608.1};
OS Metarhizium acridum (strain CQMa 102).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655827 {ECO:0000313|Proteomes:UP000002499};
RN [1] {ECO:0000313|EMBL:EFY86608.1, ECO:0000313|Proteomes:UP000002499}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CQMa 102 {ECO:0000313|EMBL:EFY86608.1,
RC ECO:0000313|Proteomes:UP000002499};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
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DR EMBL; GL698543; EFY86608.1; -; Genomic_DNA.
DR RefSeq; XP_007813726.1; XM_007815535.1.
DR AlphaFoldDB; E9EBY8; -.
DR STRING; 655827.E9EBY8; -.
DR ESTHER; metar-e9etp6; Acidic_Lipase.
DR GeneID; 19251697; -.
DR KEGG; maw:MAC_07386; -.
DR eggNOG; KOG2624; Eukaryota.
DR HOGENOM; CLU_024238_0_0_1; -.
DR InParanoid; E9EBY8; -.
DR OMA; AYCTNDD; -.
DR OrthoDB; 5471104at2759; -.
DR Proteomes; UP000002499; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR006693; AB_hydrolase_lipase.
DR PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR PANTHER; PTHR11005:SF160; STEROL ESTERASE 1-RELATED; 1.
DR Pfam; PF04083; Abhydro_lipase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:EFY86608.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002499};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 166..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 473..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 267..347
FT /note="Partial AB-hydrolase lipase"
FT /evidence="ECO:0000259|Pfam:PF04083"
FT REGION 233..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 687 AA; 77933 MW; B59BCF22DFA9D4E8 CRC64;
MAKPSIAKKP SGQKVCGAPG HELTQLGIQI KSQAGKTTQQ DHAGRTESVI IATQALITDP
ALHSLQNNDE LPTFPLTATT RVRDEVNGFV PDGGHHEKVT VEHAEAASFL KRRVHEPQAS
ATLCYSADEE TRQKNQHDNH LSDVNPLFPP LPLYGPPSFK SRLQYFVFRL SAAVLSLSFL
CFIVIASLIT SIPRLIKKII YKSTQRDIRK LRPFYEEELR RADIRKQKQK AWDHRTSAEK
IGGDQEGTAD EYPPTEGGRD KIVCDVGYYA RRVGLDVDAF KVRTEDGFLI DLWHVYDPKE
YTTPNTDTET PDTNSPGKIL KSSDKKTKFP VLLMHGLLQS SGAYCSNDDD SLAFWLCKSG
FDVWLGNNRC GFSPDHESFS PTDPRMWCWN IRQMGIFDLP ALTAQVLAET GFDKLGLICH
SQGTAETLIA LSKDQCPTLG EKLTVFCGLA PAAYAGPIID KFYFKFMRNI SPFWFQFIFG
IHAFIPFMMQ MHSLMNPTIF GWLGYKVFSF LFNWSDARWD RGLRNRLFQF APVYVSVETM
RWWLGQDGFA KHKCILSTKE DLQFEEQQDN NGPHNGSLPS SDQWYNELVP PIAMWVCGND
QLVDGKRLLR RFTNGQEPHV KMIHSKVIED YEHLDVIWAI DAVEQVFIEI REVLWKTCHA
RDRCRVPEGC EAIPAWTPGI DSTTTVI
//
