ID E9EQW8_METRA Unreviewed; 912 AA.
AC E9EQW8;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 04-MAR-2015, sequence version 2.
DT 22-FEB-2023, entry version 41.
DE SubName: Full=Glycoside hydrolase family 3 {ECO:0000313|EMBL:EFZ02624.2};
GN ORFNames=MAA_02206 {ECO:0000313|EMBL:EFZ02624.2};
OS Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium
OS anisopliae (strain ARSEF 23)).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655844 {ECO:0000313|EMBL:EFZ02624.2, ECO:0000313|Proteomes:UP000002498};
RN [1] {ECO:0000313|EMBL:EFZ02624.2, ECO:0000313|Proteomes:UP000002498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
RN [2] {ECO:0000313|EMBL:EFZ02624.2, ECO:0000313|Proteomes:UP000002498}
RP GENOME REANNOTATION.
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFZ02624.2}.
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DR EMBL; ADNJ02000001; EFZ02624.2; -; Genomic_DNA.
DR RefSeq; XP_007818395.2; XM_007820204.2.
DR AlphaFoldDB; E9EQW8; -.
DR GeneID; 19256492; -.
DR KEGG; maj:MAA_02206; -.
DR HOGENOM; CLU_008392_3_0_1; -.
DR OrthoDB; 2732849at2759; -.
DR Proteomes; UP000002498; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR PANTHER; PTHR30480:SF8; PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04060)-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EFZ02624.2};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 644..665
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..356
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 912 AA; 99033 MW; 3789BC59CF352053 CRC64;
MAAANLNPKK PNSSSSSDGS DLDPLWQNLD WAVGQMLIMG WDGTEVTPQI KSLIEDHHLG
SIILTAKNLK SAQETAKLVQ ELQTIAKNAG HPQPLLIAVD QENGGVNSLF DEDYVCQFPS
AMGIAATGRV ELAYEIYKAT ASEISACGVN LMLGPVLDVL NNARYQPLGV RSTGDDPQEA
SQYGLAALNG IRDAGIAAAG KHFPSYGNLD FQGSNSAVPV ITQTLEELSL SALVPFRNAI
ATGKLDAMFV GGCGISNPSM NVGHACLSDQ VVDDLLRNEL GFKGVAISEC LEMEALSHDL
GVQNGVVMAV EAGCDLVLLC RAYDVQLEAI KGLKLGYENG IITKDRIFTS IRRVQHLKST
CTSWAKALNP PGISLLSQLH PSHVSLSRRA YDESITVIRD KEKMLPLSSS MHPGEELLLL
TPLVKPLPAS AMTKSLLESK KTWSQAPTQH DSWAHKDRER SAIMSGEGVF LHENLIARAS
CIIIVTADAN RNMYQAGFTK HVDMMCSMHR SRGNKKQLIV VAVSSPYDFA MDKSIGTYIC
TFDFTEDAMS ALVRVLVGEI TPIGSMPGTL RKSKKVLKSR QHWLVEEYDR ARDYGGLEDL
LKAVHRASAP DLHFLKSTRA ASMELHLPNI KETHFVVRNS STGALYGFVA TYFIAGVGII
GALLVDPSKR NVSIGRSLHR RALKSLSQQR GLKKVQVGMS FPGVFLGIPL DPEANTVKEW
FSNSGWDTQF PRRLTNMIIH DLPNWVAPEG LLQSIQRANI SFDLIHGLEN AESVLHHVRA
NANPEVLELY TYALSENKTC GIVRAKDPSG NLIGTVVICR QGSPLVTYIP PLLSDGEDVG
GIIAPIVPST PQATLVLQGL ALMGVRQSKG HRASKAVLSW IVDDAFEPLV AMGFDILQAF
EEITNSPEVC QT
//
