ID E9EUK1_METRA Unreviewed; 614 AA.
AC E9EUK1;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=alpha-L-fucosidase {ECO:0000256|ARBA:ARBA00012662};
DE EC=3.2.1.51 {ECO:0000256|ARBA:ARBA00012662};
GN ORFNames=MAA_03700 {ECO:0000313|EMBL:EFZ01104.1};
OS Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium
OS anisopliae (strain ARSEF 23)).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655844 {ECO:0000313|EMBL:EFZ01104.1, ECO:0000313|Proteomes:UP000002498};
RN [1] {ECO:0000313|EMBL:EFZ01104.1, ECO:0000313|Proteomes:UP000002498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
RN [2] {ECO:0000313|EMBL:EFZ01104.1, ECO:0000313|Proteomes:UP000002498}
RP GENOME REANNOTATION.
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC carbohydrate moieties of glycoproteins.
CC {ECO:0000256|ARBA:ARBA00004071}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 29 family.
CC {ECO:0000256|ARBA:ARBA00007951}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFZ01104.1}.
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DR EMBL; ADNJ02000003; EFZ01104.1; -; Genomic_DNA.
DR RefSeq; XP_007819889.1; XM_007821698.1.
DR AlphaFoldDB; E9EUK1; -.
DR GeneID; 19257986; -.
DR KEGG; maj:MAA_03700; -.
DR HOGENOM; CLU_002934_4_2_1; -.
DR OrthoDB; 2955544at2759; -.
DR Proteomes; UP000002498; Unassembled WGS sequence.
DR GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR016286; FUC_metazoa-typ.
DR InterPro; IPR000933; Glyco_hydro_29.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR Pfam; PF01120; Alpha_L_fucos; 1.
DR PRINTS; PR00741; GLHYDRLASE29.
DR SMART; SM00812; Alpha_L_fucos; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EFZ01104.1};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..614
FT /note="alpha-L-fucosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025350195"
SQ SEQUENCE 614 AA; 68776 MW; C909E6ABC1B6BD59 CRC64;
MTRNALFAKL LTCLPGVTAL VNSVSQNSIP TRAALTRQVN LDTHESPTGL QINKPNITSK
WIDGSDLVQI VEVYINNTDP TNYLTEADNL VVEVLSDSVD TVVRGTLKRL GPRQAAIVQI
GIKNKPKAKA GSQCTGIIVA NYGHKRGGKQ ATQPVSGTCG FIDYTATKSS VNPHLAPDWF
DDLKYGIFIH WGPYAVPAYG NVGKNENYAE WYWSSMQYPN DKTQTYQYHL KTYGKDVNYD
DFFANFTDRG FDPQEWVNLF SDAGAQYFVP TTKHHDGFAL FNFSTAISKR SSIHYGPKRD
IIKDLFAAAK KYQPHLRLGT YFSMPEWFNP AYKKYGFSAW PGGPPTNPYT KAEIPYTGFV
EVKDFVKDIQ LPQMRTLADE YGIDIMWCDI TSKGNNATIF ASEWLNSARK NKRQVTFNNR
CGILGDFDTP EYVTNGETVT RKWEASRGMD PHSYGYNAQT PDSAYLTGEQ IVHTLVDMVS
KNGNFLLDIG PTGNGSIPQI MQNNLRDAGR WIKSHGESIF GTRFWTVKPG SDPFRYTTTK
DAFYIHHIGK PSETLDITDP VPYLPGDKVT VVGGRLNGKT VPASWNEVGS LKLTLGKDVL
SGDRYIWTFK IQYN
//
