ID E9FCR0_METRA Unreviewed; 697 AA.
AC E9FCR0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Ribonuclease H-like protein {ECO:0000313|EMBL:EFY94480.1};
GN ORFNames=MAA_10059 {ECO:0000313|EMBL:EFY94480.1};
OS Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium
OS anisopliae (strain ARSEF 23)).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655844 {ECO:0000313|EMBL:EFY94480.1, ECO:0000313|Proteomes:UP000002498};
RN [1] {ECO:0000313|EMBL:EFY94480.1, ECO:0000313|Proteomes:UP000002498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
RN [2] {ECO:0000313|EMBL:EFY94480.1, ECO:0000313|Proteomes:UP000002498}
RP GENOME REANNOTATION.
RC STRAIN=ARSEF 23 / ATCC MYA-3075 {ECO:0000313|Proteomes:UP000002498};
RX PubMed=25368161; DOI=10.1073/pnas.1412662111;
RA Hu X., Xiao G., Zheng P., Shang Y., Su Y., Zhang X., Liu X., Zhan S.,
RA St Leger R.J., Wang C.;
RT "Trajectory and genomic determinants of fungal-pathogen speciation and host
RT adaptation.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:16796-16801(2014).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFY94480.1}.
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DR EMBL; ADNJ02000017; EFY94480.1; -; Genomic_DNA.
DR RefSeq; XP_007826248.1; XM_007828057.1.
DR AlphaFoldDB; E9FCR0; -.
DR GeneID; 19264345; -.
DR KEGG; maj:MAA_10059; -.
DR HOGENOM; CLU_009123_10_2_1; -.
DR OrthoDB; 1877368at2759; -.
DR Proteomes; UP000002498; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR InterPro; IPR008906; HATC_C_dom.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR003656; Znf_BED.
DR PANTHER; PTHR46481:SF4; ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 39; 1.
DR PANTHER; PTHR46481; ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF05699; Dimer_Tnp_hAT; 1.
DR Pfam; PF02892; zf-BED; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 45..95
FT /note="BED-type"
FT /evidence="ECO:0000259|Pfam:PF02892"
FT DOMAIN 595..677
FT /note="HAT C-terminal dimerisation"
FT /evidence="ECO:0000259|Pfam:PF05699"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 697 AA; 79485 MW; D69C3433753CEBA4 CRC64;
MSSQRSDTLS RLDSDPLETL DSPVLNPTLS SPSITTSTVT KRRYSKVWHY TPVDRNEVTL
NALGKSIWRC KYCAKEYLES GGTTVISAHL KGRHNIDISS SQEARTTLMQ ATIADAFEKA
RQTTNYKRRC LSTVATQDLD PAVVEQLYVR WITTCSVSFR MATLSEFRAL LCYLNPEIDN
WLPNSTPTIR TWALRTFEAQ KHQVKRDIQS ALSKVHFTVD LWTSPNALAI LGIVAHYTSE
TGRLKYSVLA LRELDGKHSG PNMADCVMEV ISDYGIASKV GYFMMDNADN NSTMMKAIST
LLLDQYQIVY DAEHHRLRCN GHIINLAAQS FLFHTNDESL ADENNTSALT TPTELEMEQW
RGKGPLGKLH NIVVYIQRST QRLANFRELS GGRNLVRDNS TRWNSWYAMI RTATKLKAAI
NLFCHQYQEN NDDLLSEKDW QDLQKLQDFL LFFYDATTGT EGRNATIDRV LPTMDFLLEQ
FETAKETYAN DPFMSPCCNS GWAKLDKYYS LTDRSPVYIA ALVLSPQWKW DYIDNNWPSD
WREPCRKQML DFWTKEYKST AVAVPMQASE AGNGVKNSFY QWAQQRRGTS LDQDEYTKYL
LAPIVPEVTD PRSWWLEPTQ RKSYPALSIM ALDVLSIPAM SAEPERLFSG TKITITDRRN
RMGIESIEAT ECLKSWLGKG SRVAFADDDL DTSEAIP
//
