ID E9FLA6_9STRE Unreviewed; 634 AA.
AC E9FLA6;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Gram-positive signal peptide protein, YSIRK family {ECO:0000313|EMBL:EFX59265.1};
DE Flags: Fragment;
GN ORFNames=HMPREF0851_00237 {ECO:0000313|EMBL:EFX59265.1};
OS Streptococcus sp. M334.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=563038 {ECO:0000313|EMBL:EFX59265.1, ECO:0000313|Proteomes:UP000003840};
RN [1] {ECO:0000313|EMBL:EFX59265.1, ECO:0000313|Proteomes:UP000003840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M334 {ECO:0000313|EMBL:EFX59265.1,
RC ECO:0000313|Proteomes:UP000003840};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Earl A., Feldgarden M., Gevers D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Borenstein D., Chapman S.B., Chen Z., Engels R.,
RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA Heiman D.I., Hepburn T.A., Howarth C., Jen D., Larson L., Mehta T.,
RA Park D., Pearson M., Richards J., Roberts A., Saif S., Shea T.D.,
RA Shenoy N., Sisk P., Stolte C., Sykes S.N., Walk T., White J., Yandava C.,
RA Sibley C.D., Field T.R., Grinwis M., Eshaghurshan C.S., Surette M.G.,
RA Haas B., Nusbaum C., Birren B.;
RT "The Genome Sequence of Streptococcus sp. M334.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL732486; EFX59265.1; -; Genomic_DNA.
DR AlphaFoldDB; E9FLA6; -.
DR HOGENOM; CLU_431860_0_0_9; -.
DR OrthoDB; 2237760at2; -.
DR Proteomes; UP000003840; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR NCBIfam; TIGR01168; YSIRK_signal; 1.
DR Pfam; PF04650; YSIRK_signal; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 10..35
FT /note="YSIRK Gram-positive signal peptide"
FT /evidence="ECO:0000259|Pfam:PF04650"
FT REGION 55..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 612..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 381..408
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 55..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..103
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..118
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 634
FT /evidence="ECO:0000313|EMBL:EFX59265.1"
SQ SEQUENCE 634 AA; 69129 MW; 44B43F6AE754078E CRC64;
MFYKDNHNRE KQLRFSIRKV SFGAASVAVA ALLMFLGNGA VEASEQQHST NEAILEVTSP
NRDESISTVS KTNEGSTEAD KKNPVEQNNH PLAKSEKENR ESVISTDTPT TLNTEENQEK
PAVLKRVRRS NPDSGMDSST TNDDPSANKV FEAPAEGASL DELKAKLNEL EDSVENNDKI
RDMNTVGNSK QVKKGAVNEI NEFAGWKAVT ENGETGKFAI ARKTEGGVFP LETVNTVRTI
KGNYEYYYDT YVREQAFDRT GDYMLFLSKV RTLADREEPT FDGQSYKENG EGNGIAKGVK
GFNGIEKTFK AYSSETGSTV KISFKTGYSG DINGGKAKYK VEVMIDENGV KKTIYTKTFS
PTDNKKDDDA IITPAKDGNK REYLRNEYNN KTLDKEQVEA KMAEEQNKPN GTPGTFTSKN
IVLPKGVTDY TVRISSADNQ RLGMGYQSPH NHYALPISGL EFSISQDTSN LAKNLLQRIY
NKLKETESTD KSQKTGDSAS NYENKLNEID ALLKSSDLKT TAEYKRLSLD LLNAKEQLKE
VTPDAPTVAS DEANARVTVT PSADADRVEV TVGNSTVVAT KTGSTWSLSP AKDGVSVDPT
NGVITVAHNA ASAGTQVSAT AKHGNSDAST ASTA
//
