ID   E9FNI5_9STRE            Unreviewed;       252 AA.
AC   E9FNI5;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=RNA methyltransferase, TrmH family {ECO:0000313|EMBL:EFX58386.1};
GN   ORFNames=HMPREF0851_01405 {ECO:0000313|EMBL:EFX58386.1};
OS   Streptococcus sp. M334.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=563038 {ECO:0000313|EMBL:EFX58386.1, ECO:0000313|Proteomes:UP000003840};
RN   [1] {ECO:0000313|EMBL:EFX58386.1, ECO:0000313|Proteomes:UP000003840}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M334 {ECO:0000313|EMBL:EFX58386.1,
RC   ECO:0000313|Proteomes:UP000003840};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ward D., Earl A., Feldgarden M., Gevers D., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A.M., Borenstein D., Chapman S.B., Chen Z., Engels R.,
RA   Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA   Heiman D.I., Hepburn T.A., Howarth C., Jen D., Larson L., Mehta T.,
RA   Park D., Pearson M., Richards J., Roberts A., Saif S., Shea T.D.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S.N., Walk T., White J., Yandava C.,
RA   Sibley C.D., Field T.R., Grinwis M., Eshaghurshan C.S., Surette M.G.,
RA   Haas B., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Streptococcus sp. M334.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GL732489; EFX58386.1; -; Genomic_DNA.
DR   AlphaFoldDB; E9FNI5; -.
DR   eggNOG; COG0566; Bacteria.
DR   HOGENOM; CLU_021322_3_2_9; -.
DR   Proteomes; UP000003840; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd18095; SpoU-like_rRNA-MTase; 1.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR   InterPro; IPR001537; SpoU_MeTrfase.
DR   InterPro; IPR013123; SpoU_subst-bd.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   PANTHER; PTHR43191:SF16; RNA METHYLASE-RELATED; 1.
DR   PANTHER; PTHR43191; RRNA METHYLTRANSFERASE 3; 1.
DR   Pfam; PF00588; SpoU_methylase; 1.
DR   Pfam; PF08032; SpoU_sub_bind; 1.
DR   SMART; SM00967; SpoU_sub_bind; 1.
DR   SUPFAM; SSF75217; alpha/beta knot; 1.
DR   SUPFAM; SSF55315; L30e-like; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:EFX58386.1};
KW   Transferase {ECO:0000313|EMBL:EFX58386.1}.
FT   DOMAIN          35..101
FT                   /note="RNA 2-O ribose methyltransferase substrate binding"
FT                   /evidence="ECO:0000259|SMART:SM00967"
SQ   SEQUENCE   252 AA;  27585 MW;  36227D2A63FD0A47 CRC64;
     MCYNISMTII TSKANSVVKN AKKLHQKKYR KSAYLIEGWH LFEEAVQAGV TIEKIFALEN
     YRDQLASFPQ TVWVSEDILL DLADSQTPQG IVAVVQKEEV GEADFSQGKF LFLEDVQDPG
     NVGTIIRTAD AAGFTGVIVS DKSADIYSLK TLRSMQGSHF HLPIYRMSSQ ALLEKAKKAG
     ISVLATTLSK DSVDYRELPP IENFVLVMGN EGQGISSLMA ESADQLVHIS MKGQAESLNV
     AVAAGILIFH LS
//