ID E9GW67_DAPPU Unreviewed; 1233 AA.
AC E9GW67;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=Period circadian protein {ECO:0000256|ARBA:ARBA00040849};
GN Name=PER {ECO:0000313|EMBL:EFX76293.1};
GN ORFNames=DAPPUDRAFT_322497 {ECO:0000313|EMBL:EFX76293.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX76293.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX76293.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
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DR EMBL; GL732569; EFX76293.1; -; Genomic_DNA.
DR AlphaFoldDB; E9GW67; -.
DR SMR; E9GW67; -.
DR STRING; 6669.E9GW67; -.
DR EnsemblMetazoa; EFX76293; EFX76293; DAPPUDRAFT_322497.
DR KEGG; dpx:DAPPUDRAFT_322497; -.
DR eggNOG; KOG3753; Eukaryota.
DR HOGENOM; CLU_002704_0_0_1; -.
DR InParanoid; E9GW67; -.
DR OMA; SYPSCTQ; -.
DR PhylomeDB; E9GW67; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0001222; F:transcription corepressor binding; IBA:GO_Central.
DR GO; GO:0032922; P:circadian regulation of gene expression; IBA:GO_Central.
DR GO; GO:0043153; P:entrainment of circadian clock by photoperiod; IBA:GO_Central.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR022728; Period_circadian-like_C.
DR PANTHER; PTHR11269; PERIOD CIRCADIAN PROTEIN; 1.
DR PANTHER; PTHR11269:SF16; PERIOD CIRCADIAN PROTEIN; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF14598; PAS_11; 1.
DR Pfam; PF12114; Period_C; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Biological rhythms {ECO:0000256|ARBA:ARBA00023108};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 267..316
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 467..503
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 1..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 392..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 716..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1030..1112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1180..1233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 716..739
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 749..782
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1062..1112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1180..1214
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1233 AA; 133091 MW; 1B14DFFF8698DA15 CRC64;
MSENDGSSKS SSGPSSGSSR MDSAGSGAGS SAGNSHSIGA PSSHAESDSF QHSHMSSLKG
TSNCNISATS DSAYGGSISN SQSQRSGSGS GSRSSKSQIS SNSSNNAGAQ QLPKLRKEKD
PKKRKSKQAS IPPVQSPGLT VDRPASAGSN KAAASAAAVI SATSLAMANV FTVEGGDLVT
TSGPSPSDST GFSSGTGASI GGSAGIASAT NQSISSSKCG KEDATTSSWR SIIDPLESSL
KKTFAHLEEV PTVKSKEAFI AAISLQDGIV VYVTPSLTEK LGYPVEMWCG RSLLDFIHPK
DRLAFTNQIT SKLLASLDKD DSSSGYSFSS DEGLFPRGSM IGSSSSPPNM LCCRLRMYRG
LRTSGFGIVD KKTSYLPFKI ILNLEKITLP RESPESQNDK ETVAEGSVPK NPEEDDSDSA
EYYLLAYAVP ISTAYKNPDE KNSTGEFGLR HSANCLFSEV DMSSVPYLGH LPQDLLGTSA
LDFYHPNDLP ELKKIYDSVI GRQGKSLRSK PYNFRAFNGC YVLLQTDWTC FVNPWTKKLE
FVAGHHRVLK GPSNPDVFAN PPEGTVPFVD SDPTAAENTK KLHAEICTIL TGSAKPPHQA
RTSHNRVDTA LLETATRRRK NLATLMGSLI DEVAKARGSN SCGNSCSSST YARCKPQLHS
PAEEGSLLGD ASVVMGDIST HGGSAFDSNS ADTPLSYSLL NYNQNLERYF QSQPKMIIGS
GSGDSKQGKN QTPNMSSEEE GGCLGTDDTF SGTLPSTDSQ KLSSSNSNSI SNSRSTDSQN
GMPYEAGFKG LPLTKEAMAR HNEEMEKEFM QQHRDLRNRS TPGHRCGPAH CRKDLQGVKR
GQAASWEEGG AGGRHKHPHM DAFCATPHCY QSPLTGAATG PFNDWASLTS PSLIPSNLLP
PFSVSATMPN QQSPLFSIPM TNRGEVTNSL PAFYLATSAG ATSSGIRSNN GMSMGPSPYM
VQNEHHHQSL GPAFSLQPYA AYPHGVIYQP VMVPPMLFQP GLGMMMSPSP SMTQPQSSRH
RPFIHQNYQS ENRHRQPQPY RLSSGHVDNP VAGPSYRDDG AANANSIEQQ NSSYRQQFRE
ASGSRQQGTE QYGSNQAQNQ AQGPSNQQRP TCKRIPPWME AVSVSNELVY QYQIPGRNST
DVLEADRERL RLLQQPVMLN HQLMQLYTEM EAEQRNGIDL ALDDSENSIS SRDTDETNHR
RRELRRRSNE FRRTMLYEEN APFPHPESSS TDG
//
