ID E9H5F0_DAPPU Unreviewed; 366 AA.
AC E9H5F0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=DAPPUDRAFT_325740 {ECO:0000313|EMBL:EFX73016.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX73016.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX73016.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL732594; EFX73016.1; -; Genomic_DNA.
DR AlphaFoldDB; E9H5F0; -.
DR STRING; 6669.E9H5F0; -.
DR EnsemblMetazoa; EFX73016; EFX73016; DAPPUDRAFT_325740.
DR KEGG; dpx:DAPPUDRAFT_325740; -.
DR eggNOG; ENOG502QR1N; Eukaryota.
DR HOGENOM; CLU_053399_0_0_1; -.
DR InParanoid; E9H5F0; -.
DR OMA; IQEHANQ; -.
DR PhylomeDB; E9H5F0; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR CDD; cd16563; RING-HC_RNF220; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031824; RNF220_mid.
DR InterPro; IPR040178; RNF220_RING.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13459:SF1; E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1; 1.
DR PANTHER; PTHR13459; UNCHARACTERIZED; 1.
DR Pfam; PF15926; RNF220; 2.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}; Reference proteome {ECO:0000313|Proteomes:UP000000305};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 314..353
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 45..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..86
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..131
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 366 AA; 40820 MW; 2140FDF55541E14B CRC64;
MSATTGRKKS PLDPSCCPVC GITLRSSDLE VHFVQELERL ERVSRTFRSS SHHHHHHHGS
SGGRSISPSG SSGAMSAPAA TSQVQKREQD TRWETFHRIR INRTNRVRAK ARKRRADERE
DTPENGHHHP HLHHAAMGGG NAGSSSGSSS TPCPICGQRM YGSAEELNQH VVQCLRRNGE
DADEDEPLDV EGDSYEEYEW AGQRRIRAST MLEGGFGGVG MHICKAGDEE TEDVVVDGDD
TAAFGQPQFN EHDIQTAAAD HTSQEEGIIK CERDAQMSSA YKETDSKDHI INALKNRVCD
LEEMNKEAKQ KNRCLICLGD YRQPVVSTSC WHVHCEECWL QALGNKKLCP QCNLITSPTH
LRRIYM
//
